NCT02474615

Brief Summary

Thirty teeth twelve patients, two female and a male, who had persistent periradicular lesions were selected to participate in this study. The lesions were diagnosed with cone-beam computed tomography (cone-beam CT; Model i-Cat 17-19, Imaging Sciences International LLC).In patients with two teeth to be treated, a tooth was retroobturado with PBEA cement, (experiment) and another tooth was retroobturado with MTA cement (control). There was significance for the two cements on the repair of wounds. Key words: Apicoectomy; Oral Surgery; Biocompatible Materials; Dental Cements; Translational Medical Research

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for phase_1

Timeline
Completed

Started Feb 2013

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2013

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2014

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2015

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 24, 2015

Completed
4 months until next milestone

First Posted

Study publicly available on registry

June 18, 2015

Completed
Last Updated

June 18, 2015

Status Verified

June 1, 2015

Enrollment Period

1.5 years

First QC Date

February 24, 2015

Last Update Submit

June 17, 2015

Conditions

Mandibular Hypoplasia

Keywords

ApicoectomyOral surgeryBiocompatible materialsDental CementsTranslational Medical Research

Outcome Measures

Primary Outcomes (1)

  • Regeneration measured by tomographers endodontic surgery

    Six months after surgery, there were new scans to evaluate the repair or not the wounds.

    Six months after surgery

Study Arms (2)

TOOTH ENDODONTIC SURGERY - PBEA

EXPERIMENTAL

Endodontic surgery 15 teeth - PBEA

Procedure: ENDODONTIC SURGERY

TOOTH ENDODONTIC SURGERY -MTA

EXPERIMENTAL

Endodontic surgery 15 teeth - MTA

Procedure: ENDODONTIC SURGERY

Interventions

ENDODONTIC SURGERYPROCEDURE

ENDODONTIC SURGERY

TOOTH ENDODONTIC SURGERY - PBEATOOTH ENDODONTIC SURGERY -MTA

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • patients were diagnosed by computed tomography CT, cone beam
  • each of them had from two to four compromised teeth

You may not qualify if:

  • patients who did not return for review after six months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (4)

  • da Silva SR, da Silva Neto JD, Veiga DF, Schnaider TB, Ferreira LM. Portland cement versus MTA as a root-end filling material. A pilot study. Acta Cir Bras. 2015 Feb;30(2):160-4. doi: 10.1590/S0102-865020150020000011.

    PMID: 25714696BACKGROUND

  • Silva Neto JD, Schnaider TB, Gragnani A, Paiva AP, Novo NF, Ferreira LM. Portland cement with additives in the repair of furcation perforations in dogs. Acta Cir Bras. 2012 Nov;27(11):809-14. doi: 10.1590/s0102-86502012001100011.

    PMID: 23117614RESULT

  • Feldman AM. Does academic culture support translational research? Clin Transl Sci. 2008 Sep;1(2):87-8. doi: 10.1111/j.1752-8062.2008.00046.x. No abstract available.

    PMID: 20443823RESULT

  • Silva Neto JD, Brito RH, Schnaider TB, Gragnani A, Engelman M, Ferreira LM. Root perforations treatment using mineral trioxide aggregate and Portland cements. Acta Cir Bras. 2010 Dec;25(6):479-84. doi: 10.1590/s0102-86502010000600004.

    PMID: 21120277RESULT

MeSH Terms

Conditions

Micrognathism

Condition Hierarchy (Ancestors)

Jaw AbnormalitiesJaw DiseasesMusculoskeletal DiseasesMaxillofacial AbnormalitiesCraniofacial AbnormalitiesMusculoskeletal AbnormalitiesStomatognathic DiseasesStomatognathic System AbnormalitiesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and Abnormalities

Study Officials

  • Daniela Francescato Veiga

    BRAZIL, UNIVAS

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Aplicability clinic of cement Portland structural additived white in surgery paraendodontic

Study Record Dates

First Submitted

February 24, 2015

First Posted

June 18, 2015

Study Start

February 1, 2013

Primary Completion

August 1, 2014

Study Completion

January 1, 2015

Last Updated

June 18, 2015

Record last verified: 2015-06