NCT02472093

Brief Summary

The aim of the investigators study was to measure reductions in chronic pain in female patients with Fibromylgia comparing individual proprioceptive rehabilitation treatments with perceptual surfaces to a group exercises rehabilitation. Fibromyalgia is a generalized chronic pain condition that is usually accompanied by fatigue, sleep disturbance and psychological and cognitive alterations.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
88

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2012

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2012

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2012

Completed
11 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2013

Completed
2.1 years until next milestone

First Submitted

Initial submission to the registry

June 6, 2015

Completed
9 days until next milestone

First Posted

Study publicly available on registry

June 15, 2015

Completed
Last Updated

June 15, 2015

Status Verified

May 1, 2012

Enrollment Period

1 month

First QC Date

June 6, 2015

Last Update Submit

June 10, 2015

Conditions

Keywords

Postural exerciseBack painTender pointsFibromyalgiaPerceptive rehabilitation

Outcome Measures

Primary Outcomes (1)

  • Change of Fibromyalgia Assessment Scale (FAS) from baseline to 12 weeks

    It is a simple and rapidly implemented index, consisting of a pain map, called the Self-Assessment Pain Scale (SAPS) (in which the patient is asked to indicate how much pain he suffered in the previous week in 16 areas of the body, with scored from 0 to 3), and 2 scales (between 0 and 10) that evaluate fatigue and quality of sleep, scored from 0-10. The FAS allows physicians to obtain reliable information concerning the course of the disease and is sufficiently sensitive to alert them in case of deterioration.

    baseline, 4 weeks, 12 weeks

Secondary Outcomes (2)

  • Change of Fibromyalgia Impact Questionnaire (FIQ) from baseline to 12 weeks

    baseline, 4 weeks, 12 weeks

  • Change of Health Assessment Questionnaire (HAQ) from baseline to 12 weeks

    baseline, 4 weeks, 12 weeks

Study Arms (3)

Physical exercises treatment

ACTIVE COMPARATOR

The types of exercises included: low-impact to moderate aerobic training (gradually starting from 50% of the Fc max to 70%-80% of Fc max); walking fast in a circle, alternating with periods of going up and down the stairs (3 steps for 10 minutes) for a total of 20 consecutive minutes; posture exercises for the back and proprioceptive exercises for the trunk in the supine position to improve axial stability, including diaphragmatic breathing.

Other: Physical exercises treatment

Perceptive Rehabilitation Treatment

EXPERIMENTAL

Perceptual surfaces is a therapeutic system that is based on the interaction between the patient's back or painful area and a support surface, composed of small latex cones with various dimensions (height: 3-8 cm; base diameter: 2-4 cm) and elasticities. The inferior bases of these cones are applied to a rigid wood surface using elastic strips; usually, over 100 cones are used for each session. Patients were asked to lie down supine on the surface that was formed by the smoothed apex of these cones, creating reaction forces to the patient's weight, generated by the interaction with the cones.

Other: Perceptive Rehabilitation Treatment

Control group

ACTIVE COMPARATOR

The control group did brief educational sessions.

Other: Control group

Interventions

Includes different types of exercises: low-impact to moderate aerobic training; walking fast in a circle, alternating with periods of going up and down the stairs (3 steps for 10 minutes) for a total of 20 consecutive minutes; posture exercises for the back and proprioceptive exercises for the trunk in the supine position to improve axial stability, including diaphragmatic breathing. The heart rate was monitored through the use of a heart rate monitor, which allowed not to exceed the threshold.

Also known as: Rehabilitation Group Exercises
Physical exercises treatment

therapeutic system that is based on the interaction between the patient's back or painful area and a support surface, composed of small latex cones with various dimensions (height: 3-8 cm; base diameter: 2-4 cm) and elasticities. The inferior bases of these cones are applied to a rigid wood surface using elastic strips.

Also known as: Perceptual surfaces
Perceptive Rehabilitation Treatment

The control group did brief educational sessions.

Control group

Eligibility Criteria

Age18 Years - 60 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • fibromyalgia diagnosed according to the criteria proposed by the American College of Rheumatology (ACR 1990 and 2010)
  • Subjects aged between 18 and 60 years
  • visual analog scale (VAS) for pain \> 5

You may not qualify if:

  • presence of concomitant autoimmune diseases
  • psychiatric disorders
  • other causes of chronic pain
  • other diseases that prevented physical loading
  • severe scoliosis or kyphoscoliosis
  • surgery of the spine
  • vertebral fractures
  • sciatic pain
  • tumors
  • enrolled in another type of physical therapy program
  • myocardial infarction
  • lower extremity arterial disease
  • major neurological problems
  • diabetes
  • gastrointestinal disease
  • +3 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

FibromyalgiaPainBack Pain

Interventions

Control Groups

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesRheumatic DiseasesNeuromuscular DiseasesNervous System DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Epidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Study Officials

  • Vincenzo Maria Saraceni

    Umberto I Hospital, Sapienza University of Rome

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
medical director

Study Record Dates

First Submitted

June 6, 2015

First Posted

June 15, 2015

Study Start

May 1, 2012

Primary Completion

June 1, 2012

Study Completion

May 1, 2013

Last Updated

June 15, 2015

Record last verified: 2012-05