NCT02468479

Brief Summary

Chest/abdominal wall varices and spider nevi are two common presenting signs of liver cirrhosis. Their prognostic values remain unclear.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2015

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2015

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

June 4, 2015

Completed
6 days until next milestone

First Posted

Study publicly available on registry

June 10, 2015

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

April 19, 2017

Status Verified

April 1, 2017

Enrollment Period

1.5 years

First QC Date

June 4, 2015

Last Update Submit

April 18, 2017

Conditions

Liver Cirrhosis

Keywords

Liver cirrhosis

Outcome Measures

Primary Outcomes (4)

  • Prevalence and type of chest/abdominal wall varices and spider nevi

    Baseline data

    1.5 years

  • Association between etiology of liver cirrhosis and type of chest/abdominal wall varices and spider nevi

    Baseline data

    1.5 years

  • Association between degree of liver function and type of chest/abdominal wall varices and spider nevi

    Baseline data

    1.5 years

  • Effect of chest/abdominal wall varices and spider nevi on survival

    Follow-up data

    2.5 years or more

Interventions

No relevant intervention.OTHER

No relevant intervention.

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with a diagnosis of liver cirrhosis who are consecutively admitted to our department.

You may qualify if:

  • Liver cirrhosis.
  • Consecutive admission.
  • Permitted to physical examinations.
  • Informed consents.

You may not qualify if:

  • Non-cirrhotic portal hypertension.
  • Malignancy.
  • Uncontrolled infection.
  • Severe chronic diseases.
  • Poor patient compliance.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Department of Gastroenterology, General Hospital of Shenyang Military Area

Shenyang, Liaoning, 110840, China

Location

Related Publications (1)

  • Li H, Wang R, Mendez-Sanchez N, Peng Y, Guo X, Qi X. Impact of spider nevus and subcutaneous collateral vessel of chest/abdominal wall on outcomes of liver cirrhosis. Arch Med Sci. 2019 Mar;15(2):434-448. doi: 10.5114/aoms.2018.74788. Epub 2018 Mar 28.

    PMID: 30899297DERIVED

MeSH Terms

Conditions

Liver Cirrhosis

Condition Hierarchy (Ancestors)

Liver DiseasesDigestive System DiseasesFibrosisPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Xiaozhong Guo, MD, PhD

    Department of Gastroenterology, General Hospital of Shenyang Military Area

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Doctor

Study Record Dates

First Submitted

June 4, 2015

First Posted

June 10, 2015

Study Start

June 1, 2015

Primary Completion

December 1, 2016

Study Completion

December 1, 2016

Last Updated

April 19, 2017

Record last verified: 2017-04

Locations

CN(1)