NCT02467803

Brief Summary

Fractures of the proximal humerus and the humeral head are most common injuries and the management is challenging. Functional therapy with short immobilization, followed by an accelerated physiotherapy protocol, is a simple, convenient, noninvasive, and efficient management option. This prospective randomized study is aim to assess the function of the upper extremity of patients who will be assigned to nonoperative treatment of a proximal humeral fracture. The primary objective is the Constant score. Secondary objectives are the Disabilities of the Arm, Shoulder, and Hand (DASH) instrument, measurement of shoulder range of motion (ROM), pain and depression level with Beck Depression Scale.

Trial Health

50
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P50-P75 for early_phase_1

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 26, 2015

Completed
6 days until next milestone

Study Start

First participant enrolled

June 1, 2015

Completed
9 days until next milestone

First Posted

Study publicly available on registry

June 10, 2015

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2016

Completed
Last Updated

June 10, 2015

Status Verified

May 1, 2015

Enrollment Period

7 months

First QC Date

May 26, 2015

Last Update Submit

June 5, 2015

Conditions

Keywords

humeral fractureexercisemusculoskeletal manipulations

Outcome Measures

Primary Outcomes (1)

  • Constant Score

    Patients will be followed for 6 months. The differences between baseline score and at the end of 6 months score will be assessed.

Study Arms (2)

Intervention

ACTIVE COMPARATOR

We applied scapula mobilization with shoulder ROM exercises

Other: Scapula mobilizationOther: Shoulder ROM exercises

Control

OTHER

We applied only shoulder ROM exercises

Other: Shoulder ROM exercises

Interventions

Intervention
ControlIntervention

Eligibility Criteria

Age30 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients will be recruited if they have radiologically proven, closed fracture of the humerus according to American Orthopedics and Neer classification.

You may not qualify if:

  • skeletally immature patients
  • patients presenting to the hospital 10 days or more after injury
  • patients with open fractures or multiple trauma
  • pre-existing illness affecting the function of the upper limb, such as multiple sclerosis, paraplegia, and others
  • patients with a history of drug or alcohol abuse
  • patients with cooperation problems or problems in attending all scheduled study visits.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Handoll HH, Elliott J, Thillemann TM, Aluko P, Brorson S. Interventions for treating proximal humeral fractures in adults. Cochrane Database Syst Rev. 2022 Jun 21;6(6):CD000434. doi: 10.1002/14651858.CD000434.pub5.

MeSH Terms

Conditions

Humeral FracturesMotor Activity

Condition Hierarchy (Ancestors)

Arm InjuriesWounds and InjuriesFractures, BoneBehavior

Central Study Contacts

Hande Guney, PhD

CONTACT

Study Design

Study Type
interventional
Phase
early phase 1
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD

Study Record Dates

First Submitted

May 26, 2015

First Posted

June 10, 2015

Study Start

June 1, 2015

Primary Completion

January 1, 2016

Last Updated

June 10, 2015

Record last verified: 2015-05