Measurement of Insertion of Extraocular Muscles Using Anterior Segment Optical Coherence Tomography

NCT02454920 | Completed DMC

• 1 other identifier: 20150332
• Study Type: observational
• Target: 72
• Locations: 0 countries
• Sites: N/A

Brief Summary

Study designed to determine the ability and accuracy of anterior segment optical coherence tomography (AS-OCT) to measure the distance between the corneoscleral limbus and the insertion site of the extraocular muscles (EOM) in adults with and without previous strabismus surgery. And to compare in surgical patients the pre-operative AS-OCT limbal-muscle insertion distance measurement to the intraoperative limbal-muscle insertion measurement using calipers (gold standard).

Conditions

Strabismus; Tomography, Optical Coherence

Keywords

Strabismus; Optical Coherence Tomography; Extraocular muscles

Outcome Measures

Primary Outcomes (1)

• Limbus to extraocular muscles insertion distance

  Measurement of the limbus to insertion distance with OCT

  Baseline measurement

Secondary Outcomes (1)

• Comparison between intra operative and OCT measurements of the distance from the limbus to extraocular muscles insertion

  From date of baseline to date of surgery

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients age greater then 18 years undergoing a strabismus evaluation at the Bascom Palmer Eye Institute

You may qualify if:

• All patients age ≥ 18 years undergoing a strabismus evaluation at the Bascom Palmer Eye Institute will be invited to participate. Members of the study team will be involved in the clinical evaluation. The physician will determine if the patient has strabismus and whether strabismus surgery is advisable.

You may not qualify if:

• Patient who is unwilling to participate the study.
• A clinical scenario in which AS-OCT examination is not likely to be successful (e.g. an uncooperative patient).

Sponsors & Collaborators

• University of Miami: lead

Related Publications (3)

• Liu X, Wang F, Xiao Y, Ye X, Hou L. Measurement of the limbus-insertion distance in adult strabismus patients with anterior segment optical coherence tomography. Invest Ophthalmol Vis Sci. 2011 Oct 28;52(11):8370-3. doi: 10.1167/iovs.11-7752.

  PMID: 21948556 BACKGROUND

• Park KA, Lee JY, Oh SY. Reproducibility of horizontal extraocular muscle insertion distance in anterior segment optical coherence tomography and the effect of head position. J AAPOS. 2014 Feb;18(1):15-20. doi: 10.1016/j.jaapos.2013.11.005.

  PMID: 24568976 BACKGROUND

• Dai S, Kraft SP, Smith DR, Buncic JR. Ultrasound biomicroscopy in strabismus reoperations. J AAPOS. 2006 Jun;10(3):202-5. doi: 10.1016/j.jaapos.2006.01.209.

  PMID: 16814170 BACKGROUND

MeSH Terms

Conditions

Strabismus

Condition Hierarchy (Ancestors)

Ocular Motility Disorders; Cranial Nerve Diseases; Nervous System Diseases; Eye Diseases

Study Officials

• Hilda Capo, MD

  Professor

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Target Duration: 12 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Clinical

Study Record Dates

• First Submitted: May 19, 2015
• First Posted: May 27, 2015
• Study Start: May 1, 2015
• Primary Completion: December 1, 2015
• Study Completion: January 1, 2016
• Last Updated: July 2, 2017

Record last verified: 2017-06

Data Sharing

• IPD Sharing: Will not share