NCT02448706

Brief Summary

The goal of this project is to find out if the way a hearing aid processes a sound signal should be determined in part by an individual's cognitive characteristics. We anticipate that the outcome of this work will be a battery of assessments that will guide hearing aid processing for older patients with hearing loss.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
49

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 15, 2015

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 19, 2015

Completed
1 month until next milestone

Study Start

First participant enrolled

July 1, 2015

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2017

Completed
2.5 years until next milestone

Results Posted

Study results publicly available

January 14, 2020

Completed
Last Updated

November 17, 2020

Status Verified

October 1, 2020

Enrollment Period

2 years

First QC Date

May 15, 2015

Results QC Date

June 9, 2019

Last Update Submit

October 23, 2020

Conditions

Keywords

hearing aid

Outcome Measures

Primary Outcomes (1)

  • Speech Intelligibility Score

    Participants listen to sentences in a background of noise and repeat the sentence heard. The outcome is percentage of correctly repeated words.

    6 weeks

Secondary Outcomes (3)

  • Effectiveness of Aural Rehabilitation (EAR)

    6 weeks

  • Speech and Spatial Qualities of Hearing (SSQ) Questionnaire

    6 weeks

  • Adherence

    6 weeks

Study Arms (2)

Hearing Aid Fitting Order A

ACTIVE COMPARATOR

High level of signal manipulation for 6 weeks, followed by a low level of signal manipulation for 6 weeks.

Device: Hearing Aid Fitting ADevice: Hearing Aid Fitting B

Hearing Aid Fitting Order B

ACTIVE COMPARATOR

Low level of signal manipulation for 6 weeks, followed by a low level of signal manipulation for 6 weeks.

Device: Hearing Aid Fitting ADevice: Hearing Aid Fitting B

Interventions

Also known as: Hearing Aid
Hearing Aid Fitting Order AHearing Aid Fitting Order B
Hearing Aid Fitting Order AHearing Aid Fitting Order B

Eligibility Criteria

Age54 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Sensorineural Hearing loss with pure-tone thresholds 25-70 dB HL at octave frequencies between 250 and 4000 Hz, 4 frequency PTA of ≥ 30 dB HL
  • Non hearing aided wearer within the previous year
  • Participants will be in good health (self-report)
  • Normal or corrected to normal vision(≤20/50)

You may not qualify if:

  • Conductive, or asymmetric hearing loss
  • Hearing loss exceeding the limits that can be successfully aided with hearing aids (i.e., profound hearing loss)
  • Hearing loss remediated with a cochlear implant (cannot wear hearing aids)
  • Significant history of otologic or neurologic disorders
  • Non English speaking participants
  • Score of 23 or below on Mini-Mental Status Exam (MMSE)
  • Score of 22 or below on Montreal Cognitive Assessment (MoCA)
  • Any clinically significant unstable or progressive medical condition
  • Any condition which, in the opinion of the investigator, places the participant at unacceptable risk if he or she were to participate in the study.
  • Participants will be divided into low and high working groups based upon the results of their Lunner working memory reading span test. Once either high or low working memory group is filled (approximately 25 participants) we will selectively enroll participants to fill the other category.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Colorado at Boulder

Boulder, Colorado, 80309, United States

Location

Related Publications (1)

  • Anderson M, Rallapalli V, Schoof T, Souza P, Arehart K. The use of self-report measures to examine changes in perception in response to fittings using different signal processing parameters. Int J Audiol. 2018 Nov;57(11):809-815. doi: 10.1080/14992027.2018.1490035. Epub 2018 Jul 27.

MeSH Terms

Conditions

Hearing LossPresbycusis

Interventions

Hearing Aids

Condition Hierarchy (Ancestors)

Hearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsHearing Loss, Sensorineural

Intervention Hierarchy (Ancestors)

Wearable Electronic DevicesElectrical Equipment and SuppliesEquipment and SuppliesSensory Aids

Results Point of Contact

Title
Pamela Souza
Organization
Northwestern University

Study Officials

  • Pamela E Souza, PhD

    Northwestern University

    PRINCIPAL INVESTIGATOR
  • Kathryn H Arehart, PhD

    University of Colorado at Boulder

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor School of Communication

Study Record Dates

First Submitted

May 15, 2015

First Posted

May 19, 2015

Study Start

July 1, 2015

Primary Completion

July 1, 2017

Study Completion

July 1, 2017

Last Updated

November 17, 2020

Results First Posted

January 14, 2020

Record last verified: 2020-10

Locations