NCT02442999

Brief Summary

Randomized clinical trial among women with polycystic ovary syndrome (PCOS) who present for fertility treatment to evaluate the impact of screening for obstructive sleep apnea.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2016

Geographic Reach
1 country

6 active sites

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 13, 2015

Completed
1 month until next milestone

First Posted

Study publicly available on registry

May 13, 2015

Completed
8 months until next milestone

Study Start

First participant enrolled

January 1, 2016

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2017

Completed
Last Updated

May 4, 2017

Status Verified

May 1, 2017

Enrollment Period

1.3 years

First QC Date

April 13, 2015

Last Update Submit

May 1, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Ovulatory cycles

    3 months

Study Arms (2)

Usual care

NO INTERVENTION

Screen for Sleep Apnea

EXPERIMENTAL

Screen for sleep apnea, treat with continuous positive airway pressure (CPAP) if diagnosed with sleep apnea

Other: Screening for obstructive sleep apneaDevice: CPAP - continuous positive airway pressure

Interventions

Screen for Sleep Apnea
Screen for Sleep Apnea

Eligibility Criteria

Age18 Years - 50 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Females 18 - 50 years old.
  • Receiving care from an Obstetrician / gynecologist or a Reproductive endocrinology infertility specialist
  • Polycystic ovarian syndrome defined by the modified Rotterdam criteria
  • Able to speak and understand as well as give informed consent in English

You may not qualify if:

  • Late onset congenital adrenal hyperplasia
  • Cushings disease
  • Androgen-secreting tumors
  • Previous diagnosis of obstructive sleep apnea
  • Current use of over the counter or prescribed sleep medications.
  • Examples of medications that exclude a patient from this study include but are not limited to Unisom, Ambien or Lunesta.
  • Patients who are taking non-prescribed herbal medications for sleep will not be excluded from the study. Examples of these include but are not limited to melatonin, chamomile, or valerian.
  • Untreated thyroid disease
  • Prolactin excess
  • Patients with the following medical conditions will be excluded from the study as portable sleep apnea monitors are not indicated in patients with severe pulmonary disease, neuromuscular disease, or congestive heart failure.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

USF REI Lakeland

Lakeland, Florida, 33805, United States

Location

USF REI Sarasota

Sarasota, Florida, 34239, United States

Location

USF REI St. Petersburg

St. Petersburg, Florida, 33701, United States

Location

USF South Tampa Center

Tampa, Florida, 33606, United States

Location

USF Morsani

Tampa, Florida, 33612, United States

Location

USF REI Wesley Chapel

Wesley Chapel, Florida, 33544, United States

Location

MeSH Terms

Conditions

Sleep Apnea Syndromes

Interventions

Mass ScreeningContinuous Positive Airway Pressure

Condition Hierarchy (Ancestors)

ApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Intervention Hierarchy (Ancestors)

Diagnostic Techniques and ProceduresDiagnosisHealth SurveysSurveys and QuestionnairesData CollectionEpidemiologic MethodsInvestigative TechniquesDiagnostic ServicesPreventive Health ServicesHealth ServicesHealth Care Facilities Workforce and ServicesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public HealthPublic Health PracticePositive-Pressure RespirationRespiration, ArtificialAirway ManagementTherapeuticsRespiratory Therapy

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 13, 2015

First Posted

May 13, 2015

Study Start

January 1, 2016

Primary Completion

May 1, 2017

Study Completion

May 1, 2017

Last Updated

May 4, 2017

Record last verified: 2017-05

Locations