NCT02440503

Brief Summary

The investigators research group conducted a feeding study in 2012 (IRB 07-0003) that included breastfed infants consuming different infant solid foods. The investigators results showed that different solid foods, especially the protein content of the food, is important on infant's gut bacteria profile and growth. Although the first year of life is critical in obesity development later in life, data are very limited on the effect of protein from solid foods, an important component of infant diet, especially in breast-fed infants. In this study, the investigators will re-contact these participants, who are now in their early childhood (\~5 years old), to evaluate the long-term effect of various macronutrient quantities in solid foods, by assessing the participants' growth, body composition, and gut bacteria profile.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
75

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2014

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2014

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

June 25, 2014

Completed
11 months until next milestone

First Posted

Study publicly available on registry

May 12, 2015

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2017

Completed
Last Updated

October 26, 2017

Status Verified

October 1, 2017

Enrollment Period

3.2 years

First QC Date

June 25, 2014

Last Update Submit

October 24, 2017

Conditions

Outcome Measures

Primary Outcomes (2)

  • Age adjusted height

    observational, one time assessment. The hospital visit is scheduled according to the participant's availability.

    Day 1: one time assessment during the participant's visit to Colorado Children's hospital

  • Age adjusted weight

    observational, one time assessment. The hospital visit is scheduled according to the participant's availability.

    Day 1: one time assessment during the participant's visit to Colorado Children's hospital

Secondary Outcomes (1)

  • Percent body fat

    Day 1: one time assessment during the participant's visit to Colorado Children's hospital

Eligibility Criteria

Age4 Years - 7 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Children 4-6 years of age

You may qualify if:

  • Those participants who completed the initial trial when they were infants.

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UC Denver

Aurora, Colorado, 80045, United States

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

stool samples will be collected for microbiome analysis

Study Officials

  • Minghua Tang, PhD

    University of Colorado, Denver

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 25, 2014

First Posted

May 12, 2015

Study Start

June 1, 2014

Primary Completion

August 1, 2017

Study Completion

August 1, 2017

Last Updated

October 26, 2017

Record last verified: 2017-10

Locations