NCT02439047

Brief Summary

The objective of this study, which will be realised in vitro on human samples, is to test 2 cell sources isolated from peritoneum for adult mesothelial cells (peritoneal samples) and from adipose tissue for the adipose stem cells (adipose tissue samples). The latter will be differentiated towards the mesothelial phenotype and morphotype. The 2 routes will be compared and the most satisfactory one will be chosen to make a non-stick patch.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
6

participants targeted

Target at below P25 for not_applicable cancer

Timeline
Completed

Started Jun 2015

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 23, 2015

Completed
15 days until next milestone

First Posted

Study publicly available on registry

May 8, 2015

Completed
24 days until next milestone

Study Start

First participant enrolled

June 1, 2015

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2015

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2016

Completed
Last Updated

March 16, 2026

Status Verified

March 1, 2026

Enrollment Period

5 months

First QC Date

April 23, 2015

Last Update Submit

March 12, 2026

Conditions

Cancer

Keywords

reconstructive surgeryabdominal surgery

Outcome Measures

Primary Outcomes (1)

  • Morphotype/Phenotype expression

    Mesothelial morphotype and phenotype expression of the 2 types of cells after culture

    1 year

Study Arms (1)

Biological samples collection

EXPERIMENTAL

-Peritoneal samples : will be collected during abdominal surgery A biopsy from 1 to 2 cm2 will be performed in healthy peritoneum -Adipose tissue samples : will be collected during surgery for breast reconstruction

Procedure: Biological samples collection

Interventions

Biological samples collectionPROCEDURE

-Peritoneal samples : will be collected during abdominal surgery A biopsy from 1 to 2 cm2 will be performed in healthy peritoneum \- Adipose tissue samples : will be collected during surgery for breast reconstruction

Biological samples collection

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Aged more than 18 years old,
  • Planned surgery For peritoneal samples : abdominal surgery (laparotomy or coelioscopy) For adipose tissue samples : breast reconstructive surgery (lipomodelage)
  • Informed and signed consent

You may not qualify if:

  • Pregnant or breastfeeding woman
  • Patient under guardianship or tutorship
  • For peritoneal samples : previous abdomino-pelvic radiotherapy or abdominal surgery ; peritoneal carcinosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Centre Oscar Lambret

Lille, 59020, France

Location

MeSH Terms

Conditions

Neoplasms

Study Officials

  • Lucie BRESSON, MD

    Centre Oscar Lambret

    PRINCIPAL INVESTIGATOR

  • Feng Chai, MD

    INSERM U1008

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 23, 2015

First Posted

May 8, 2015

Study Start

June 1, 2015

Primary Completion

November 1, 2015

Study Completion

November 1, 2016

Last Updated

March 16, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)