NCT02438319

Brief Summary

Manually and automatically by mashing learning algorithm optic disc will be evaluated (planimetry).

Trial Health

15
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Jul 2017

Typical duration for all trials

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 29, 2015

Completed
9 days until next milestone

First Posted

Study publicly available on registry

May 8, 2015

Completed
2.2 years until next milestone

Study Start

First participant enrolled

July 1, 2017

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 20, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 20, 2020

Completed
Last Updated

March 26, 2020

Status Verified

March 1, 2020

Enrollment Period

2.7 years

First QC Date

April 29, 2015

Last Update Submit

March 24, 2020

Conditions

Open Angle Glaucoma

Outcome Measures

Primary Outcomes (1)

  • agreement measured by kappa statistics

    agreement measured by kappa statistics

    Baseline visit in the outpatient department

Secondary Outcomes (4)

  • Cup size

    Baseline visit in the outpatient department

  • size of excavation

    Baseline visit in the outpatient department

  • vertical cup to disc ratio

    Baseline visit in the outpatient department

  • rim area

    Baseline visit in the outpatient department

Study Arms (1)

patients with open angle glaucoma

patients with open angle glaucoma who had their optic discs routinely documented by fundus photography. Optic disc photographs will be analyzied by manual planimetry or automated planimetry.

Other: manual planimetryOther: automated planimetry

Interventions

manual planimetryOTHER

Manually marking of the boundaries of the optic disc and it's excavation on color photographs of the optic disc.

patients with open angle glaucoma
automated planimetryOTHER

Automatic detection of the boundaries of the optic disc and it's excavation on color photographs of the optic disc.

patients with open angle glaucoma

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients with a diagnosis of open-angle glaucoma

You may qualify if:

  • open-angle glaucoma

You may not qualify if:

  • no fundus photography of the optic disc performed

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Jonas JB. [Glaucoma diagnosis of the optic disc using photography and planimetry]. Ophthalmologe. 2003 Jan;100(1):13-20. doi: 10.1007/s00347-002-0752-4. German.

    PMID: 12557021BACKGROUND

MeSH Terms

Conditions

Glaucoma, Open-Angle

Condition Hierarchy (Ancestors)

GlaucomaOcular HypertensionEye Diseases

Study Officials

  • Jens Funk, MD, PhD

    University of Zurich

    PRINCIPAL INVESTIGATOR
0

Study Design

Study Type
observational
Observational Model
CASE CROSSOVER
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 29, 2015

First Posted

May 8, 2015

Study Start

July 1, 2017

Primary Completion

March 20, 2020

Study Completion

March 20, 2020

Last Updated

March 26, 2020

Record last verified: 2020-03

Data Sharing

IPD Sharing
Will not share