Alcohol Hand Gel Use in Mbale Regional Referral Hospital: a Cost Effectiveness Evaluation

NCT02435719 | Completed

• 1 other identifier: SAfRI/OBS/001
• Study Type: observational
• Target: 3,626
• Locations: 1 country
• Sites: 1

Brief Summary

Ministry of Health through the National Medical Stores has supplied alcohol-based handgels to the different health facilities in Uganda for the health care providers to use during clinical care. However, constant stock-outs and or limited supplies remains the main constraint faced by the hospitals. Thus the handgels are generally used by a few of the senior health care providers. The promotion of bedside, antiseptic handrubs largely contributes to the increase in compliance and sustained improvement of hand hygiene compliance reduces Health care acquired infections (HCAIs), but it is not yet established how cost- effective the intervention is in a a rural Ugandan hospital where funds are severely rationed and, which serves over 4 million people in over 15 districts in Uganda. An evaluation of an intervention's cost-effectiveness is a crucial factor in whether the government will be prepared to fund the intervention and sustain it. This WardGel study thus aims to assess the cost-benefit of providing hand gel for all health care workers in Mbale Regional Referral Hospital.

Conditions

Infections, Hospital

Keywords

HCAIs; Handgel; Hospital; Effectiveness

Outcome Measures

Primary Outcomes (1)

• Evidence of Hospital acquired infection confirmed clinically

  Hospital acquired infection will be defined as new clinically diagnosed infection developed whilst an inpatient or within 2 days of discharge (for readmitted patients).

  At least 48 hours after hospital admission or re-admission.Participants will be followed for the duration of hospital stay, an expected average of 5 days.

Secondary Outcomes (3)

• Evidence of Hospital Acquired infection confirmed by laboratory investigations (CBC and C&S)

  At least 48 hours after admission or readmission.Participants will be followed for the duration of hospital stay, an expected average of 5 days.

• Hand hygiene compliance by health care providers based on the WHO's 5-moments of Hand hygiene

  during patient clinical care.participants will be observed during their clinical care practice, an expected average of 30 minutes per session

• cost-effectiveness of hand gel use by micro-economic assessment

  Additional period due to confirmed hospital acquired infection.Participants will be followed for the duration of hospital stay, an expected average of 5 days.

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study population will include in-patients and health care providers on six (6) selected wards (Labour ward, Postnatal ward, Gynaecological ward, Acute Care unit, paediatric Ward, and general surgical wards) The sample will be selected by convenience non-probability sampling method

You may qualify if:

• Patients is admitted for at least 24 hours
• Any health care provider, including students

You may not qualify if:

• Patients discharged before 24 hours

Sponsors & Collaborators

• Sanyu Africa Research Institute: lead
• Mbale Regional Referral Hospital: collaborator
• University of Liverpool: collaborator
• Nagasaki University: collaborator

Study Sites (1)

Mbale Regional Referral hospital

Mbale, Uganda

Location

Related Publications (1)

• Saito H, Inoue K, Ditai J, Wanume B, Abeso J, Balyejussa J, Weeks A. Alcohol-based hand rub and incidence of healthcare associated infections in a rural regional referral and teaching hospital in Uganda ('WardGel' study). Antimicrob Resist Infect Control. 2017 Dec 28;6:129. doi: 10.1186/s13756-017-0287-8. eCollection 2017.

  PMID: 29299303 DERIVED

MeSH Terms

Conditions

Cross Infection

Condition Hierarchy (Ancestors)

Infections; Iatrogenic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Andrew Weeks, PhD

  University of Liverpool

  PRINCIPAL INVESTIGATOR

• James Ditai, MPH

  Sanyu Africa Research Institute

  PRINCIPAL INVESTIGATOR

• Benon Wanume, MMED (CP)

  Mbale Regional Referral Hospital

  PRINCIPAL INVESTIGATOR

• Julian Abeso, MMED (Paed)

  Mbale Regional Referral Hospital

  STUDY DIRECTOR

• Kyoko Inoue, MPH

  Nagasaki University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 20, 2015
• First Posted: May 6, 2015
• Study Start: October 1, 2014
• Primary Completion: May 1, 2015
• Study Completion: May 1, 2015
• Last Updated: October 13, 2016

Record last verified: 2016-10

Locations

UG (1)