Dietary Phosphate and Serum Phosphorus

NCT02435017 | Completed

• 1 other identifier: Pro00001798
• Study Type: observational
• Target: 7,895
• Locations: 0 countries
• Sites: N/A

Brief Summary

Overall study design is to review National Health and Nutrition Examination Survey (NHANES) data 1999-2008 for nutrition risk according to kidney function. Substudies will be performed to review the association of nutrients and overall dietary intake compared to biomarkers available in NHANES during this period.

Conditions

Phosphorus Metabolism Disorders

Keywords

kidney disease; recommended dietary allowances; nutrition assessment; food; dietary proteins; Vitamin D; dietary fats; ethnology; Continental Population Groups; Phosphorus, dietary; Phosphorus/analysis

Outcome Measures

Primary Outcomes (1)

• Serum phosphorus concentration

  Serum phosphorus concentration on the day that 24-hour dietary recall was obtained (reflecting dietary intake the day prior to blood draw); measured in mg/dL

  approximately 24 hours

Secondary Outcomes (1)

• Kidney function level

  Baseline

Study Arms (1)

Adults 20-85 years

Data from adults 20-85 years old will be evaluated for serum phosphorus concentration.

Eligibility Criteria

• Age: 20 Years - 85 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Participants in the continuous NHANES program from 2003-2006 who met the inclusion/exclusion criteria were included in the analysis. NHANES samples the general US population to determine prevalence of major diseases and health risks by combining physical examination with laboratory studies and questionnaires in a standardized environment using trained personnel. Participants are selected through a complex, multistage, probability sampling approach.

You may qualify if:

• Serum creatinine

You may not qualify if:

• Pregnancy
• No dietary intake interview
• Dietary intake interview not valid
• Answered the question "Have you had dialysis in the past year?" as "Yes"

Sponsors & Collaborators

• Linda W. Moore: lead
• The Methodist Hospital Research Institute: collaborator

Related Publications (2)

• Moore LW, Byham-Gray LD, Scott Parrott J, Rigassio-Radler D, Mandayam S, Jones SL, Mitch WE, Osama Gaber A. The mean dietary protein intake at different stages of chronic kidney disease is higher than current guidelines. Kidney Int. 2013 Apr;83(4):724-32. doi: 10.1038/ki.2012.420. Epub 2013 Jan 9.

  PMID: 23302719 BACKGROUND

• Moore LW, Nolte JV, Gaber AO, Suki WN. Association of dietary phosphate and serum phosphorus concentration by levels of kidney function. Am J Clin Nutr. 2015 Aug;102(2):444-53. doi: 10.3945/ajcn.114.102715. Epub 2015 Jun 3.

  PMID: 26040641 DERIVED

MeSH Terms

Conditions

Phosphorus Metabolism Disorders; Kidney Diseases

Condition Hierarchy (Ancestors)

Metabolic Diseases; Nutritional and Metabolic Diseases; Urologic Diseases; Female Urogenital Diseases; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases; Male Urogenital Diseases

Study Officials

• Linda W Moore, MS

  Director, Clinical Trials; Dept of Surgery

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Sponsor-Investigator/Principal Investigator

Study Record Dates

• First Submitted: April 22, 2015
• First Posted: May 6, 2015
• Study Start: January 1, 2003
• Primary Completion: December 1, 2006
• Study Completion: July 1, 2009
• Last Updated: September 17, 2018

Record last verified: 2018-09