NCT02433847

Brief Summary

Effect of mosapride 30mg/day on the small bowel and colon transit time in patients with chronic constipation or constipated irritable bowel syndrome.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for phase_4

Timeline
Completed

Started May 2015

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 13, 2015

Completed
18 days until next milestone

Study Start

First participant enrolled

May 1, 2015

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 5, 2015

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2016

Completed
8 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

May 5, 2015

Status Verified

April 1, 2015

Enrollment Period

11 months

First QC Date

April 13, 2015

Last Update Submit

April 29, 2015

Conditions

Keywords

mosapride

Outcome Measures

Primary Outcomes (1)

  • colonic transit time

    the change of colonic transit time after mosapride 30mg/day administration : whole colonic transit time, rt. colon / lt. colon / rectosigmoid colonic transit time

    2 weeks

Study Arms (1)

mosapride

EXPERIMENTAL
Drug: Mosapride

Interventions

mosapride

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Functional constipation or constipated irritable bowel syndrome patients according to Rome III criteria

You may not qualify if:

  • Intolerable or hypersensitive to mosapride
  • Known Parkinson's ds
  • Cardio- or cerebrovascular disease within 3 months
  • Malignancy requiring surgery or chemotherapy or radiation within 5 years
  • History of GI surgeries except hernia repair, appendectomy, primary closure due to perforation
  • Refractory diabetes mellitus/hypertension/thyroid diseases
  • Symptomatic heart failure, renal failure, arrhythmia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Interventions

mosapride

Study Design

Study Type
interventional
Phase
phase 4
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 13, 2015

First Posted

May 5, 2015

Study Start

May 1, 2015

Primary Completion

April 1, 2016

Study Completion

December 1, 2016

Last Updated

May 5, 2015

Record last verified: 2015-04