NCT02424825

Brief Summary

The purpose of this protocol is to collect data from approximately 15 multiple sclerosis (MS) patients who are participating in a pilot cooking course. This online cooking training program is currently available to general public through the company "Rouxbe" for a fee. Data gathered from this cooking course will be used to develop novel ways of promoting healthy eating habits in people with MS. The investigators will use the data from blood tests, questionnaires, and demographics to assess the feasibility and effectiveness of this program. This is an outpatient program designed for people with MS that would occur regardless of whether participant data is collected. This pilot cooking course will run for approximately four weeks. The investigators intend start to the training course in mid-March 2015. Subjects will be followed prior to course initiation for baseline data gathering, at four weeks from baseline, twelve weeks from baseline, and twenty-four weeks from baseline.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
15

participants targeted

Target at below P25 for not_applicable multiple-sclerosis

Timeline
Completed

Started Feb 2015

Shorter than P25 for not_applicable multiple-sclerosis

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2015

Completed
8 days until next milestone

First Submitted

Initial submission to the registry

February 9, 2015

Completed
2 months until next milestone

First Posted

Study publicly available on registry

April 23, 2015

Completed
8 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2015

Completed
Last Updated

April 29, 2019

Status Verified

April 1, 2019

Enrollment Period

3 months

First QC Date

February 9, 2015

Last Update Submit

April 25, 2019

Conditions

Keywords

dietcookingmultiple sclerosisfatigue

Outcome Measures

Primary Outcomes (1)

  • Program Feasibility and Efficacy (composite of student perception, learning, and adherence by surveys)

    We will measure feasibility as a composite of student perception, learning, and adherence by administering Opening and Closing Surveys (to evaluate student perception of course), a Final Assessment (to evaluate student learning), and the NutritionQuest Block Food Frequency Questionnaire (to evaluate adherence to low-fat, plant-based lifestyle).

    6 months

Secondary Outcomes (4)

  • Weight Change measured by body weight, body mass index, waist circumference

    6 months

  • Diet Change measured by NutritionQuest Block Food Frequency Questionnaire, Opening Survey, Program Evaluation Survey

    6 months

  • Program Evaluation through Program Evaluation Survey

    6 months

  • Fatigue measured by Modified Fatigue Impact Scale-5 and Fatigue Severity Scale

    6 months

Study Arms (1)

Rouxbe

EXPERIMENTAL

Subjects will attend a one-month online cooking course, and be followed before, during, and after their participation for quality-of-life, fatigue, and blood biomarker changes.

Behavioral: Cooking Course

Interventions

Cooking CourseBEHAVIORAL

This is a month-long online cooking course, aimed at promoting a low-fat, plant-based diet.

Rouxbe

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Confirmed diagnosis of MS
  • Willingness to comply with the diet and values set forth in the course

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Oregon Health & Science University Multiple Sclerosis Center.

Portland, Oregon, 97239, United States

Location

Related Publications (1)

  • Perlman J, Wu H, Fryman A, Lane M, Bittner F, Sammi MK, Rooney WD, Stevens A, Yadav V. Effects of vascular disease risk factors on brain metabolism in multiple sclerosis. Mult Scler Relat Disord. 2025 Dec;104:106700. doi: 10.1016/j.msard.2025.106700. Epub 2025 Sep 10.

Related Links

MeSH Terms

Conditions

Multiple SclerosisFatigue

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNSAutoimmune Diseases of the Nervous SystemNervous System DiseasesDemyelinating DiseasesAutoimmune DiseasesImmune System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Vijayshree Yadav, MBBs, MCR

    Oregon Health and Science University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

February 9, 2015

First Posted

April 23, 2015

Study Start

February 1, 2015

Primary Completion

May 1, 2015

Study Completion

May 1, 2015

Last Updated

April 29, 2019

Record last verified: 2019-04

Locations