NCT02421224

Brief Summary

The investigators will conduct a cluster randomized controlled trial of several behavioral interventions for smoking cessation among a sample of employees at large workplaces in the Bangkok metropolitan area. The study aims to test the impacts of different incentive structures for smoking cessation on take-up, effectiveness, and cost-effectiveness. The interventions are designed to elucidate certain principles from the field of behavioral economics.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,190

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2015

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2015

Completed
14 days until next milestone

First Submitted

Initial submission to the registry

April 15, 2015

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 20, 2015

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2017

Completed
3.3 years until next milestone

Results Posted

Study results publicly available

November 18, 2020

Completed
Last Updated

December 30, 2020

Status Verified

December 1, 2020

Enrollment Period

2.3 years

First QC Date

April 15, 2015

Results QC Date

October 26, 2020

Last Update Submit

December 3, 2020

Conditions

Keywords

Smoking CessationIncentivesHealth BehaviorSmokingWork-site

Outcome Measures

Primary Outcomes (1)

  • Proportion of Participants With Smoking Abstinence at 12 Months

    7-day point prevalence of abstinence measured 12 months after enrollment using self-reported abstinence and urine cotinine test results

    12 months after enrollment

Secondary Outcomes (3)

  • Proportion of Participants With Smoking Abstinence at 3 Months

    3 months after enrollment

  • Program Acceptance

    At 0 months (at enrollment)

  • Proportion of Participants With Smoking Abstinence at 6 Months

    6 months after enrollment

Study Arms (9)

Usual Care

ACTIVE COMPARATOR

Participants will receive in-person group counseling from a trained smoking cessation counselor. Participants will learn about reasons to quit smoking, strategies for quitting smoking, and additional resources available to support the quit attempt. Participants will also complete a quit plan.

Behavioral: Usual Care

Deposits

EXPERIMENTAL

Same as Usual Care, plus participants will have to deposit a certain amount of their own money as an incentive to quit smoking. Participants will be able to make additional voluntary deposits above the minimum amount. The participant will be refunded all deposits if he quits smoking at 3 months, as verified by a urine cotinine test. The participant will forfeit all deposits if he continues to smoke at 3 months, as verified by a urine cotinine test.

Behavioral: Usual CareBehavioral: Deposits

Small Individual Bonus

EXPERIMENTAL

Same as Usual Care, plus each participant will receive a monetary bonus from the study investigators if he or she quit smoking, as verified by a urine cotinine test.

Behavioral: Usual CareBehavioral: Small Individual Bonus

Large Individual Bonus

EXPERIMENTAL

Same as Usual Care, plus each participant will receive a monetary bonus from the study investigators if he or she quit smoking, as verified by a urine cotinine test. The bonus is twice the value of that in the Small Individual Bonus group.

Behavioral: Usual CareBehavioral: Large Individual Bonus

Team Bonus

EXPERIMENTAL

Same as Usual Care, plus each participant will be randomly assigned one teammate to provide social support during the quit attempt. If the participant and assigned teammate both quit smoking at 3 months, as verified by a urine cotinine test, then each will receive a monetary bonus. The team bonus is equal in value to that in the Large Individual Bonus group.

Behavioral: Usual CareBehavioral: TeammateBehavioral: Team Bonus

Deposits plus Small Individual Bonus

EXPERIMENTAL

Same as Usual Care, plus the participant will follow the protocol for deposits as described for the Deposits group and will follow the protocol for the monetary bonus as described for the Small Individual Bonus group.

Behavioral: Usual CareBehavioral: DepositsBehavioral: Small Individual Bonus

Deposits plus Large Individual Bonus

EXPERIMENTAL

Same as Usual Care, plus the participant will follow the protocol for deposits as described for the Deposits group and will follow the protocol for the monetary bonus as described for the Large Individual Bonus group.

Behavioral: Usual CareBehavioral: DepositsBehavioral: Large Individual Bonus

Deposits plus Teammate

EXPERIMENTAL

Same as Usual Care, plus the participant will follow the protocol for deposits as described for the Deposits group and will be randomly assigned one other participant to serve as a teammate who provides social support during the quit attempt.

Behavioral: Usual CareBehavioral: DepositsBehavioral: Teammate

Deposits plus Team Bonus

EXPERIMENTAL

Same as Usual Care, plus the participant will follow the protocol for deposits as described for the Deposits group, will be randomly assigned a teammate, and will follow the protocol for the monetary bonus as described for the Team Bonus group.

Behavioral: Usual CareBehavioral: DepositsBehavioral: TeammateBehavioral: Team Bonus

Interventions

Usual CareBEHAVIORAL

Participants will receive in-person group counseling from a trained smoking cessation counselor. Participants will learn about reasons to quit smoking, strategies for quitting smoking, and additional resources available to support the quit attempt. Participants will also complete a quit plan.

DepositsDeposits plus Large Individual BonusDeposits plus Small Individual BonusDeposits plus Team BonusDeposits plus TeammateLarge Individual BonusSmall Individual BonusTeam BonusUsual Care
DepositsBEHAVIORAL

Participants will have to deposit a certain amount of their own money at enrollment. Participants will be able to make additional voluntary deposits above the minimum amount during the intervention period. The participant will be refunded all deposits if he quits smoking at 3 months, as verified by a urine cotinine test. The participant will forfeit all deposits if he continues to smoke at 3 months, as verified by a urine cotinine test.

DepositsDeposits plus Large Individual BonusDeposits plus Small Individual BonusDeposits plus Team BonusDeposits plus Teammate

Each participant will receive a monetary bonus from the study investigators if he or she quit smoking, as verified by a urine cotinine test.

Deposits plus Small Individual BonusSmall Individual Bonus

Each participant will receive a monetary bonus from the study investigators if he or she quit smoking, as verified by a urine cotinine test. The bonus is twice the value of that in the Small Individual Bonus group.

Deposits plus Large Individual BonusLarge Individual Bonus
TeammateBEHAVIORAL

Each participant will be randomly assigned one teammate to provide social support during the quit attempt. Each participant will be assigned to a participating coworker who speaks the same primary language and works the same work shift as the participant.

Deposits plus Team BonusDeposits plus TeammateTeam Bonus
Team BonusBEHAVIORAL

If the participant and assigned teammate both quit smoking at 3 months, as verified by a urine cotinine test, then each will receive a monetary bonus. The team bonus is equal in value to that in the Large Individual Bonus group.

Deposits plus Team BonusTeam Bonus

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Current full-time employee of a participating company
  • Smoker of 100+ cigarettes during lifetime
  • Smoker of 10+ cigarettes per week
  • Individual is aged 18+ years old
  • Smoker wants to quit within the next 6 months

You may not qualify if:

  • Expects to leave company within the next 12 months
  • Is currently pregnant
  • Are unable to provide informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mahidol University

Bangkok, Thailand

Location

Related Publications (1)

  • White JS, Lowenstein C, Srivirojana N, Jampaklay A, Dow WH. Incentive programmes for smoking cessation: cluster randomized trial in workplaces in Thailand. BMJ. 2020 Oct 14;371:m3797. doi: 10.1136/bmj.m3797.

MeSH Terms

Conditions

Tobacco Use DisorderSmoking CessationHealth BehaviorSmoking

Condition Hierarchy (Ancestors)

Substance-Related DisordersChemically-Induced DisordersMental DisordersBehavior

Results Point of Contact

Title
Dr. Justin S. White
Organization
University of California, San Francisco

Study Officials

  • William H. Dow, PhD

    University of California, Berkeley

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 15, 2015

First Posted

April 20, 2015

Study Start

April 1, 2015

Primary Completion

August 1, 2017

Study Completion

August 1, 2017

Last Updated

December 30, 2020

Results First Posted

November 18, 2020

Record last verified: 2020-12

Locations