NCT02420626

Brief Summary

The Crux Vena Cava Filter (VCF) Registry is a clinical study, sponsored by Volcano Corporation, to evaluate the short and long term performance and clinical outcomes of the Crux Vena Cava Filter System.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Jan 2016

Typical duration for all trials

Geographic Reach
1 country

3 active sites

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 7, 2015

Completed
13 days until next milestone

First Posted

Study publicly available on registry

April 20, 2015

Completed
9 months until next milestone

Study Start

First participant enrolled

January 1, 2016

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2017

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2019

Completed
Last Updated

April 22, 2016

Status Verified

December 1, 2015

Enrollment Period

1.3 years

First QC Date

April 7, 2015

Last Update Submit

April 21, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Prevention of Pulmonary Embolism

    The primary objective is to evaluate the long term clinical outcomes of patients treated with the Crux VCF for the prevention of PE over a two year period or up to filter retrieval, whichever comes first.

    2 years

Eligibility Criteria

Age19 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients are eligible for inclusion if they are scheduled for a vena cava filter implant with the Crux VCF System or have had a Crux VCF implanted within the previous 6 months for any of the following situations: 1. Pulmonary thromboembolism when anticoagulation therapy is contraindicated; 2. Failure of anticoagulation therapy in thromboembolic disease; 3. Emergency treatment following massive pulmonary embolism where anticipated benefits of conventional therapy are reduced; and 4. Chronic, recurrent pulmonary embolism where anticoagulant therapy has failed or is contraindicated.

You may qualify if:

  • The patient is \>18 years of age.
  • Patient or their legally authorized representative understands the research nature of the study and is willing and capable of providing informed consent.
  • Scheduled for and receives a Crux VCF implant or;
  • Have previously had a Crux VCF implanted within the previous 6 months.

You may not qualify if:

  • Patients unwilling or unable to comply with the protocol and provide informed consent.
  • Female patient of childbearing potential who is pregnant (she must have negative pregnancy test within the 48 hours prior to implantation and any retrieval procedure)
  • Patient is participating in another device or drug clinical trial that interferes with this protocol follow up schedule.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Northside Vascular Surgery

Atlanta, Georgia, 30342, United States

Location

Rex Healthcare

Raleigh, North Carolina, 27607, United States

Location

Turkey Creek Medical Center

Knoxville, Tennessee, 37934, United States

Location

MeSH Terms

Conditions

Pulmonary EmbolismVenous ThromboembolismVenous Thrombosis

Condition Hierarchy (Ancestors)

Lung DiseasesRespiratory Tract DiseasesEmbolismEmbolism and ThrombosisVascular DiseasesCardiovascular DiseasesThromboembolismThrombosis
0

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 7, 2015

First Posted

April 20, 2015

Study Start

January 1, 2016

Primary Completion

May 1, 2017

Study Completion

May 1, 2019

Last Updated

April 22, 2016

Record last verified: 2015-12

Locations