NCT02420106

Brief Summary

The purpose of the proposed research is to determine if Osteopathic manipulative medicine (OMM) used alone or in combination with the standard treatment of botulinum toxin intramuscular injections improves motor function and quality of life amongst people with cervical (neck) dystonia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2014

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2014

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

February 18, 2014

Completed
1.2 years until next milestone

First Posted

Study publicly available on registry

April 17, 2015

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2019

Completed
Last Updated

July 2, 2019

Status Verified

July 1, 2019

Enrollment Period

5 years

First QC Date

February 18, 2014

Last Update Submit

July 1, 2019

Conditions

Keywords

cervical dystonianeck painOMMspasmodic torticollis

Outcome Measures

Primary Outcomes (1)

  • Change in Motor Function

    Motor function will be assessed by Vicon 3-Dimensional analysis of the subjects' biomechanics while walking and will depict stride length and arm swing on each side of the body as well as the posture of the shoulder and pelvic girdle with reference to the coronal, transverse and sagittal planes.

    baseline and 5 weeks

Secondary Outcomes (1)

  • Change in Quality of Life

    baseline and 5 weeks

Study Arms (2)

OMM alone

ACTIVE COMPARATOR

Subjects who are not receiving botulinum treatment consenting to Osteopathic Manipulative Medicine intervention

Procedure: Osteopathic Manipulative Medicine

OMM plus Botulinum

ACTIVE COMPARATOR

Subjects who are receiving botulinum treatment and will have osteopathic manipulative medicine intervention.

Procedure: Osteopathic Manipulative Medicine

Interventions

Osteopathic manipulative medicine involves manual technique to joints and soft tissue to improve movement.

OMM aloneOMM plus Botulinum

Eligibility Criteria

Age2 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • clinical diagnosis of cervical dystonia or spasmodic torticollis
  • ages 2-100

You may not qualify if:

  • no clinical diagnosis of cervical dystonia or spasmodic torticollis
  • symptoms beginning over the age of 40
  • pregnant women are excluded from Aim 2

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

New York Institute of Technology

Old Westbury, New York, 11568, United States

Location

MeSH Terms

Conditions

TorticollisNeck Pain

Condition Hierarchy (Ancestors)

DystoniaDyskinesiasNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsPain

Study Officials

  • Jayme Mancini, DO

    New York Institute of Technology

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 18, 2014

First Posted

April 17, 2015

Study Start

February 1, 2014

Primary Completion

February 1, 2019

Study Completion

February 1, 2019

Last Updated

July 2, 2019

Record last verified: 2019-07

Locations