NCT02419326

Brief Summary

The purpose of this study is to test the feasibility, acceptability, and preliminary efficacy of a novel couple-based intervention for binge-eating disorder (BED).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
11

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2014

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2014

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

March 31, 2015

Completed
17 days until next milestone

First Posted

Study publicly available on registry

April 17, 2015

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2016

Completed
Last Updated

October 27, 2016

Status Verified

October 1, 2016

Enrollment Period

2.1 years

First QC Date

March 31, 2015

Last Update Submit

October 25, 2016

Conditions

Keywords

couplesrelationshipsbinge eatingeating disordercouple therapy

Outcome Measures

Primary Outcomes (2)

  • Total score at Post-treatment of the Client Satisfaction Questionnaire-8 (CSQ-8)- Patient

    8-item self-report scale assessing the effectiveness of, and satisfaction with, content and format of treatment.

    Post-treatment (on average 6 months after beginning treatment)

  • Total score at Post-treatment of the Client Satisfaction Questionnaire-8 (CSQ-8)- Partner

    8-item self-report scale assessing the effectiveness of, and satisfaction with, content and format of treatment.

    Post-treatment (on average 6 months after beginning treatment)

Secondary Outcomes (54)

  • Number of patients with binge-eating remission (0 objective binge episodes over last 28 days) at post-treatment determined by Eating Disorder Examination (EDE)

    Post-treatment (on average 6 months after beginning treatment)

  • Number of patients with binge eating remission (0 objective binge-eating episodes in last 28 days) at 3-month follow-up determined by the Eating Disorder Examination (EDE)

    3-Month Follow-up

  • Change from Baseline to Post-Treatment in the Eating Disorder Examination (EDE) Binge Eating Episode Frequency Score- Patient

    Baseline, Post-Treatment (on average 6 months after beginning treatment)

  • Change from Baseline to 3-Month Follow-up in the Eating Disorder Examination (EDE) Binge Eating Episode Frequency Score- Patient

    Baseline, 3-Month Follow-up

  • Change from Baseline to Post-Treatment in the Eating Disorder Examination (EDE) Number of Days Binge Eating Score- Patient

    Baseline, Post-Treatment (on average 6 months after beginning treatment)

  • +49 more secondary outcomes

Study Arms (1)

Couples

EXPERIMENTAL

The patient and their significant other receive psychotherapy treatment for the patient's BED.

Behavioral: Psychotherapy treatment

Interventions

UNITE is a manualized, 22-session CBCT (cognitive behavioral couples therapy) intervention that engages the couple to target the core psychopathology of BED and address the uniquely challenging stress that BED places on intimate relationships.

Couples

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Participant with BED:
  • Subject currently meets criteria for BED or sub-threshold symptoms, according to the Diagnostic and Statistical Manual of Mental Disorders (5th Ed)
  • Concurrent outpatient therapy and medical monitoring
  • Health insurance coverage
  • Both members of the couple:
  • English speaking and able to read
  • Involved in a committed relationship for at least 6 months regardless of sexual orientation (couple is not required to live together)
  • Willing to participate in treatment

You may not qualify if:

  • Participant with BED:
  • \) Post-bariatric
  • Both members of the couple:
  • Alcohol or drug dependence in the last year
  • Current significant suicidal ideation
  • Severe depression that would seriously interfere with functional capacity
  • Developmental disability that would impair the ability to benefit from intervention
  • Any psychosis, schizophrenia, or bipolar I disorder, unless stably remitted on maintenance therapy for at least 1 year
  • Moderate to high levels of physical violence from either partner as reported on the Conflict Tactics Scale-2 at pre-treatment
  • Unwillingness to forgo non-protocol concurrent couples therapy
  • Previously participated in the preliminary couples treatment study UCAN: Uniting Couples (in the treatment of) Anorexia Nervosa (NCT01740752)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UNC Center of Excellence for Eating Disorders

Chapel Hill, North Carolina, 27599, United States

Location

MeSH Terms

Conditions

Binge-Eating DisorderFeeding and Eating DisordersBulimia

Condition Hierarchy (Ancestors)

Mental DisordersSigns and Symptoms, DigestiveSigns and SymptomsPathological Conditions, Signs and SymptomsHyperphagia

Study Officials

  • Cristin D Runfola, Ph.D.

    University of North Carolina, Chapel Hill

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 31, 2015

First Posted

April 17, 2015

Study Start

September 1, 2014

Primary Completion

October 1, 2016

Study Completion

October 1, 2016

Last Updated

October 27, 2016

Record last verified: 2016-10

Locations