Effects of Chest Physiotherapy (CPT) on Lung Clearance Index (LCI) in Non Cystic Fibrosis (CF) Bronchiectasis
Short-term Effects of Chest Physiotherapy on Ventilation Inhomogeneity in Non-CF Bronchiectasis
1 other identifier
interventional
24
1 country
1
Brief Summary
This study will investigate the effects of on technique of chest physiotherapy on pulmonary function. Effects of pulmonary function will be measured by the spirometry, body plethysmography and by the multiple breath nitrogen washout technique.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Apr 2015
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 1, 2015
CompletedFirst Submitted
Initial submission to the registry
April 3, 2015
CompletedFirst Posted
Study publicly available on registry
April 8, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2016
CompletedMarch 22, 2016
March 1, 2016
6 months
April 3, 2015
March 19, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Change of Lung Clearance Index (LCI)
LCI will me measured before and after the chest physiotherapy session
up to 80 minutes
Secondary Outcomes (2)
Change of Spirometry
up to 40 minutes
Sputum weight
35 minutes
Study Arms (1)
Autogenic drainage
OTHERThe autogenic drainage will be the chest physiotherapy technique used for this study. Autogenic drainage is an airway clearance technique that attempts to obtain the optimal airflow to evacuate the secretions. This technique uses modulation of inspiratory and expiratory airflow at different breathing level within the vital capacity.
Interventions
Eligibility Criteria
You may qualify if:
- Non cystic fibrosis bronchiectasis in stable state
You may not qualify if:
- Not in stable state
- Bronchiectasis with severe respiratory morbidities likely to reduce the chest physiotherapy session efficacy (e.g. : severe chronic obstructive pulmonary disease)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Cliniques universitaires Saint-Luc
Brussels, 1200, Belgium
Related Publications (1)
Poncin W, Reychler G, Leeuwerck N, Bauwens N, Aubriot AS, Nader C, Liistro G, Gohy S. Short-Term Effect of Autogenic Drainage on Ventilation Inhomogeneity in Adult Subjects With Stable Non-Cystic Fibrosis Bronchiectasis. Respir Care. 2017 May;62(5):524-531. doi: 10.4187/respcare.05194. Epub 2017 Feb 21.
PMID: 28223466DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Sophie Gohy, MD, PhD
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- PRINCIPAL INVESTIGATOR
William Poncin, PhD student
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
- STUDY CHAIR
Grégory Reychler, PhD
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Physiotherapist
Study Record Dates
First Submitted
April 3, 2015
First Posted
April 8, 2015
Study Start
April 1, 2015
Primary Completion
October 1, 2015
Study Completion
February 1, 2016
Last Updated
March 22, 2016
Record last verified: 2016-03