Trials Sponsors Conditions Drugs Pricing

Conditions

Pain, Postoperative

Keywords

postoperative painsurgerypain resolutionpain intensitypersistent postsurgical painpain-related genesanalgesic

Outcome Measures

Primary Outcomes (1)

Measure postoperative pain scores change with respect to time
Pain scores will be measured using previously established pain scale and Questionnaire
up to 7 days

Secondary Outcomes (3)

Measure variables that contribute to postoperative pain scores
up to 6 months
Measure timing patterns that may influence development of persistent postsurgical pain (PPP)
up to 6 months
Genetic testing
up to 1 day

Study Arms (1)

Surgical patients' clinical progression

Patients undergoing non-ambulatory surgery will be asked questions and complete surveys in an effort to characterize postoperative pain experience profiles. A blood sample will be obtained for genetic markers exploring a variety of pain-related genes.

Behavioral: Surgical patients' clinical progressionGenetic: Genetic markers

Interventions

Surgical patients' clinical progressionBehavioral

Study the dynamic nature of pain

Surgical patients' clinical progression

Genetic markersGenetic

Research variants in genes related to pain sensitivity, analgesic sensitivity and opioid response

Surgical patients' clinical progression

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodNon-Probability Sample

Study Population

Patients scheduled for surgery will be invited to participate in this study.

You may qualify if:

years of age or older

Sponsors & Collaborators

University of Florida
Otherlead
National Institute of General Medical Sciences (NIGMS)
NIHcollaborator

Study Sites (1)

UF Health

Gainesville, Florida, 32610-3003, United States

MeSH Terms

Conditions

Pain, PostoperativePain

Interventions

Genetic Markers

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsNeurologic ManifestationsSigns and Symptoms

Intervention Hierarchy (Ancestors)

BiomarkersBiological FactorsPhenotypeGenetic Phenomena

Study Officials

Patrick J Tighe, MD
Assistant Professor of Anesthesiology and Program Director, Perioperative Analytics Group Joint Assistant Professor of Orthopedics
PRINCIPAL INVESTIGATOR

Enrollment

428 participants (actual enrollment reported by the registry).

Study Design

Study Type: observational
Observational Model: COHORT
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

March 9, 2015

First Posted

April 3, 2015

Study Start

August 2015

Actual (reported)

TEMporal PostOperative Pain Signatures

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (1)

Surgical patients' clinical progression

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (3)

Study Arms (1)

Surgical patients' clinical progression

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Intervention Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations