NCT02407444

Brief Summary

This study aims to evaluate whether a combination of cycling training as part of physiotherapy treatment will contribute more than conventional physiotherapy treatment for elderly patients after hip fracture surgery in their subacute phase of rehabilitation.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jul 2015

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 19, 2015

Completed
15 days until next milestone

First Posted

Study publicly available on registry

April 3, 2015

Completed
3 months until next milestone

Study Start

First participant enrolled

July 1, 2015

Completed
2.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2018

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2018

Completed
Last Updated

March 22, 2016

Status Verified

March 1, 2016

Enrollment Period

2.8 years

First QC Date

March 19, 2015

Last Update Submit

March 19, 2016

Conditions

Keywords

Proximal hip fractureElderly patientsPhysiotherapyLeg cycling ergometer

Outcome Measures

Primary Outcomes (12)

  • FIM ( functional independence measure)

    Provides a uniform system of measurement for disability, it measures the level of patient's disability and indicates how much assistance is required for the individual to carry out activities of daily living. It contains 18 items composed of 13 motor tasks and 5 cognitive tasks. Tasks are rated on 7 point ordinal scale that ranges from total assistance to complete independence. Score range from 18 (lowest) to 126 (highest) indicating level of function.

    baseline-at the first day of intervention

  • Static balance test and weight bearing distribution while standing

    The balance and weight bearing distribution parameters will be evaluated by posturographic device . This system assesses pressure fluctuations produced by the heels and toes of a subject standing on four separate platforms two for each foot and their respective halves. The pressure plates emit electronic signals which are digitized and processed by the posturographic device software to yield a set of unique parameters. Calculated results based on these parameters, which are statistically and functionally independent, reflect the interactions of the various neuro-physiological and neuro-anatomic subsystems involved in balance control.

    baseline-at the first day of intervention

  • Muscle strength

    Quadriceps strength and hand grip will be assessed by hand held dynamometer. This is a quantitative and objective method for assessment of muscular strength. Scored using force production in kilograms.

    baseline-at the first day of intervention

  • Pain intensity (measured with VAS)

    Subjective pain intensity will be measured with VAS which is an 11 point scale from 0-10, "0" indicates no pain and "10" indicates the most intense pain imaginable. The patient select the value that is most in line with the intensity of pain that he experienced in the last 24 hours.

    baseline-at the first day of intervention

  • Change from baseline in FIM at 2 weeks

    Provides a uniform system of measurement for disability, it measures the level of patient's disability and indicates how much assistance is required for the individual to carry out activities of daily living. It contains 18 items composed of 13 motor tasks and 5 cognitive tasks. Tasks are rated on 7 point ordinal scale that ranges from total assistance to complete independence. Score range from 18 (lowest) to 126 (highest) indicating level of function.

    Second week of intervention

  • Change from baseline in FIM at 3 weeks

    Provides a uniform system of measurement for disability, it measures the level of patient's disability and indicates how much assistance is required for the individual to carry out activities of daily living. It contains 18 items composed of 13 motor tasks and 5 cognitive tasks. Tasks are rated on 7 point ordinal scale that ranges from total assistance to complete independence. Score range from 18 (lowest) to 126 (highest) indicating level of function.

    End of intervention at third week

  • Change from baseline in static balance test and weight bearing distribution while standing at 2 weeks

    The balance and weight bearing distribution parameters will be evaluated by posturographic device . This system assesses pressure fluctuations produced by the heels and toes of a subject standing on four separate platforms two for each foot and their respective halves. The pressure plates emit electronic signals which are digitized and processed by the posturographic device software to yield a set of unique parameters. Calculated results based on these parameters, which are statistically and functionally independent, reflect the interactions of the various neuro-physiological and neuro-anatomic subsystems involved in balance control.

    Second week of intervention

  • Change from baseline in static balance test and weight bearing distribution while standing at 3 weeks

    The balance and weight bearing distribution parameters will be evaluated by posturographic device . This system assesses pressure fluctuations produced by the heels and toes of a subject standing on four separate platforms two for each foot and their respective halves. The pressure plates emit electronic signals which are digitized and processed by the posturographic device software to yield a set of unique parameters. Calculated results based on these parameters, which are statistically and functionally independent, reflect the interactions of the various neuro-physiological and neuro-anatomic subsystems involved in balance control.

    End of intervention at third week

  • Change from baseline in muscle strength at 2 weeks

    Quadriceps strength and hand grip will be assessed by hand held dynamometer. This is a quantitative and objective method for assessment of muscular strength. Scored using force production in kilograms.

    Second week of intervention

  • Change from baseline in muscle strength at 3 weeks

    Quadriceps strength and hand grip will be assessed by hand held dynamometer. This is a quantitative and objective method for assessment of muscular strength. Scored using force production in kilograms.

    End of intervention at third week

  • Change from baseline in pain intensity at 2 weeks (measured with VAS)

    Subjective pain intensity will be measured with VAS which is an 11 point scale from 0-10, "0" indicates no pain and "10" indicates the most intense pain imaginable. The patient select the value that is most in line with the intensity of pain that he experienced in the last 24 hours.

    Second week of intervention

  • Change from baseline in pain intensity at 3 weeks (measured with VAS)

    Subjective pain intensity will be measured with VAS which is an 11 point scale from 0-10, "0" indicates no pain and "10" indicates the most intense pain imaginable. The patient select the value that is most in line with the intensity of pain that he experienced in the last 24 hours.

    End of intervention at third week

Study Arms (2)

Physiotherapy treatment & leg cycling

EXPERIMENTAL

This group will receive conventional physiotherapy treatments, each session will last 30 minutes. Treatments include muscles strength exercises for upper and lower extremities, static and dynamic balance training in standing ,pain relief techniques and functional training (including transfers, sit to stand, walking and climbing stairs). The treatment program shall be consistent with the patient's problems and the degree of difficulty will rise depending on progress. In addition this group will have cycling training with leg cycle ergometer for 20 minutes. This treatment protocol will last for three weeks, five days a week, 50 minutes each session per day.

Other: Physiotherapy treatment & leg cycling

Physiotherapy treatment & music listening

ACTIVE COMPARATOR

This group will receive conventional physiotherapy treatments, each session will last 30 minutes .Treatments include muscles strength exercises for upper and lower extremities, static and dynamic balance training in standing ,pain relief techniques and functional training (including transfers, sit to stand, walking and climbing stairs). The treatment program shall be consistent with the patient's problems and the degree of difficulty will rise depending on progress. In addition this group will listen to music (while sitting on a chair) for 20 minutes.This treatment protocol will last for three weeks, five days a week, 50 minutes each session per day.

Other: Physiotherapy treatment & music listening

Interventions

All patients receive comprehensive care as part of routine rehabilitation program : individual physical therapy treatment, gym's training and balance training in virtual reality, occupational therapy treatment, strengthening and range of motion exercises as a group. In addition each patient in this group will train with stationary leg cycle ergometer for 20 minutes under physical therapist's supervision . Cycling exercise intensity subjectively determined by the patient using RPE Borg scale . Maximal intensity level determined as 14 in Borg scale.

Physiotherapy treatment & leg cycling

All patients receive comprehensive care as part of routine rehabilitation program : individual physical therapy treatment, gym's training and balance training in virtual reality, occupational therapy treatment, strengthening and range of motion exercises as a group. In addition each patient in this group will listen to music with earphone for 20 minutes while sitting under physical therapist supervision. Overall treatment session will last 50 minutes.

Physiotherapy treatment & music listening

Eligibility Criteria

Age65 Years - 95 Years
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • Proximal hip fracture with full or partial weight bearing indication.
  • Surgical fixation ( nailing or total hip replacement or hemiarthroplasty)
  • Pre-morbid function: walking independently or under supervision with or without assistance aid
  • Cognitive function: Mini-mental state examination score above 21

You may not qualify if:

  • Pathological hip fracture.
  • Unstable heart or pulmonary disease.
  • Presence of other fractures as a result of the current fall.
  • Neurological comorbidities ( CVA, Parkinson, MS ).
  • Entering the rehabilitation center more than three weeks after hip surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

"Beit- Rivka" geriatric rehabilitation hospital

Petach Tiqva, Israel

RECRUITING

Related Publications (1)

  • Fairhall NJ, Dyer SM, Mak JC, Diong J, Kwok WS, Sherrington C. Interventions for improving mobility after hip fracture surgery in adults. Cochrane Database Syst Rev. 2022 Sep 7;9(9):CD001704. doi: 10.1002/14651858.CD001704.pub5.

MeSH Terms

Conditions

Hip Fractures

Condition Hierarchy (Ancestors)

Femoral FracturesFractures, BoneWounds and InjuriesHip InjuriesLeg Injuries

Study Officials

  • Avital Hershkovitz, MD-PhD

    Beit-Rivka Geriatric Rehabilitation Hospital

    PRINCIPAL INVESTIGATOR
  • Youssef Ma Masharawi, PhD

    Tel Aviv University

    STUDY CHAIR

Central Study Contacts

Avital Hershkovitz, MD-PhD

CONTACT

Hila Dahan, BPT

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

March 19, 2015

First Posted

April 3, 2015

Study Start

July 1, 2015

Primary Completion

May 1, 2018

Study Completion

December 1, 2018

Last Updated

March 22, 2016

Record last verified: 2016-03

Locations