NCT02404857

Brief Summary

The goal is to evaluate the potential of a EEG based BCI (Brain-Computer-Interface) connected to a non-invasive pneumatic glove for rehabilitation of hand-movements post-stroke.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
11 days until next milestone

First Submitted

Initial submission to the registry

January 12, 2015

Completed
3 months until next milestone

First Posted

Study publicly available on registry

April 1, 2015

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2015

Completed
Last Updated

November 24, 2015

Status Verified

November 1, 2015

Enrollment Period

9 months

First QC Date

January 12, 2015

Last Update Submit

November 23, 2015

Conditions

Keywords

Post strokeBCIReeducationHand movement

Outcome Measures

Primary Outcomes (1)

  • Performance of the BCI-system (evaluation of performance through patient questionaires & the performance of the BCI classifier during intended and imagined hand movements)

    Evaluation of the BCI-platform performance through patient questionnaires \& the performance of the BCI classifier during intended and imagined hand movements.

    During the whole study. Assesment is made for each patient after his participation ( 2 hours).

Secondary Outcomes (1)

  • EEG sensory-motor rhythm signals (Detailed analysis of the EEG signals in relation to the severity of the paresis and movement condition)

    During the whole studyAssesment is made for each patient after his participation ( 2 hours).

Study Arms (1)

Chronic post-stroke

EXPERIMENTAL

Patients \>6 months post-stroke with little to no hand movement. use of EEG based BCI in the neurorehabilitation process

Device: EEG based Brain Computer Interface

Interventions

Using EEG signals to classify brain activity being 'rest' or 'active' to control the attached pneumatic glove and close the sensory-motor loop between intentional/mental movement and physical (though passive) movement.

Chronic post-stroke

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • \> 6 months post-stroke (chronic), unilateral
  • \> 18 yrs
  • little to no hand movement
  • spasticity \< 3 on modified Ashworth Scale

You may not qualify if:

  • major cognitive deficits (Folstein mini mental status \> 23
  • strong hemi-neglect (Catherine Bergego scale \> 15/30)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHRU Lapeyronie

Montpellier, Herault, 34295, France

Location

MeSH Terms

Conditions

Stroke

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular Diseases

Study Officials

  • Liesjet Van Dokkum, PhD

    CHRU Montpellier, Lapeyronie // Euromov-M2H, Montpellier University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 12, 2015

First Posted

April 1, 2015

Study Start

January 1, 2015

Primary Completion

October 1, 2015

Study Completion

October 1, 2015

Last Updated

November 24, 2015

Record last verified: 2015-11

Locations