NCT02394938

Brief Summary

Aims. To describe a new conceptual framework and to test the effectiveness of a recorded music listening protocol on symptom burden and quality of life in heart failure patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
150

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 17, 2015

Completed
12 days until next milestone

Study Start

First participant enrolled

March 1, 2015

Completed
19 days until next milestone

First Posted

Study publicly available on registry

March 20, 2015

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2015

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
Last Updated

March 27, 2017

Status Verified

March 1, 2017

Enrollment Period

8 months

First QC Date

February 17, 2015

Last Update Submit

March 24, 2017

Conditions

Keywords

Music therapy

Outcome Measures

Primary Outcomes (1)

  • Changes in heart failure specific quality of life (Minnesota Living with Heart Failure Questionnaire)

    The heart failure specific quality of life will be measured with the Minnesota Living with Heart Failure Questionnaire.

    Baseline, 1st 2nd, 3th, 6th month

Secondary Outcomes (9)

  • Use of emergency services

    1st, 2nd, 3th, 6th month

  • Generic quality of life (measured with the Short Form -12.)

    Baseline, 1st 2nd, 3th, 6th month

  • Self-care (Self-Care of Heart Failure Index version 6.2)

    Baseline, 1st 2nd, 3th, 6th month

  • Somatic perception of heart failure symptoms (Heart Failure Somatic Perception Scale)

    Baseline, 1st 2nd, 3th, 6th month

  • Sleep quality (Pittsburgh Sleep Quality Index)

    Baseline, 1st 2nd, 3th, 6th month

  • +4 more secondary outcomes

Study Arms (2)

MUSIC

EXPERIMENTAL

In addition to the standard care, heart failure patients assigned to the music group will listen recorded classical music.

Other: MUSIC

CONTROL

NO INTERVENTION

Heart Failure patients assigned to the control group will receive standard care only. The standard care will consist in nursing and medical counselling, self-care education and medication.

Interventions

MUSICOTHER

In addition to the standard care,patients assigned to the music group will listen recorded classical music. Music will be delivered with a mp3 Player and headphones Music will be listened by the patient in his home.The music play list will be formed by a classical repertoire.During the intervention patients will be recommended to listen to the music for 3 months. Also patients will be asked to listen to the music once or more than once per day, at any time, for a total of 30 minutes per day.Music will be listen at 50-60 decibels below the threshold of 85 db established for listening to portable media devices such as compact disc and MP3 players.Music in this protocol will have a tempo/rhythm in a range of 60-80 beats per minute (bpm).

MUSIC

Eligibility Criteria

Age50 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • a confirmed diagnosis of heart failure according to the guidelines specified by the European Society of Cardiology ;
  • NYHA functional classification I to III, including patients with preserved ejection fraction (HFPEF) and with a reduced ejection fraction (HFREF);
  • the presence of a formal or informal caregiver;
  • signed informed consent.

You may not qualify if:

  • deafness ;
  • severe neurological disorder (Parkinson, multiple sclerosis, Alzheimer's disease;
  • severe psychiatric disorder;
  • frank dementia,
  • reduced level of consciousness.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Francesco Burrai

Bologna, Bologna, 40124, Italy

Location

Related Publications (7)

  • Bernardi L, Porta C, Casucci G, Balsamo R, Bernardi NF, Fogari R, Sleight P. Dynamic interactions between musical, cardiovascular, and cerebral rhythms in humans. Circulation. 2009 Jun 30;119(25):3171-80. doi: 10.1161/circulationaha.108.806174.

  • Chanda ML, Levitin DJ. The neurochemistry of music. Trends Cogn Sci. 2013 Apr;17(4):179-93. doi: 10.1016/j.tics.2013.02.007.

  • Fancourt D, Ockelford A, Belai A. The psychoneuroimmunological effects of music: a systematic review and a new model. Brain Behav Immun. 2014 Feb;36:15-26. doi: 10.1016/j.bbi.2013.10.014. Epub 2013 Oct 21.

  • Hanser SB. Music therapy in cardiac health care: current issues in research. Cardiol Rev. 2014 Jan-Feb;22(1):37-42. doi: 10.1097/CRD.0b013e318291c5fc.

  • Mandel SE, Hanser SB, Secic M, Davis BA. Effects of music therapy on health-related outcomes in cardiac rehabilitation: a randomized controlled trial. J Music Ther. 2007 Fall;44(3):176-97. doi: 10.1093/jmt/44.3.176.

  • Trappe HJ. The effects of music on the cardiovascular system and cardiovascular health. Heart. 2010 Dec;96(23):1868-71. doi: 10.1136/hrt.2010.209858.

  • Burrai F, Hasan W, Fancourt D, Luppi M, Di Somma S. A Randomized Controlled Trial of Listening to Recorded Music for Heart Failure Patients: Study Protocol. Holist Nurs Pract. 2016 Mar-Apr;30(2):102-15. doi: 10.1097/HNP.0000000000000135.

MeSH Terms

Conditions

Heart Diseases

Condition Hierarchy (Ancestors)

Cardiovascular Diseases

Study Officials

  • Maria Cristina Pirazzini, MSN

    AUSL Bologna

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD

Study Record Dates

First Submitted

February 17, 2015

First Posted

March 20, 2015

Study Start

March 1, 2015

Primary Completion

November 1, 2015

Study Completion

December 1, 2015

Last Updated

March 27, 2017

Record last verified: 2017-03

Locations