NCT02390388

Brief Summary

The aim of this prospective randomized study is to assess the analgesic efficacy and duration of Pudendal block compared with Caudal block for pediatric patients undergoing hypospadias surgery concerning intraoperative analgesic and also postoperative total analgesic consumption within 24 hours.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for phase_4 pain

Timeline
Completed

Started Nov 2014

Shorter than P25 for phase_4 pain

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2014

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

January 26, 2015

Completed
2 months until next milestone

First Posted

Study publicly available on registry

March 17, 2015

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2015

Completed
Last Updated

August 26, 2015

Status Verified

August 1, 2015

Enrollment Period

6 months

First QC Date

January 26, 2015

Last Update Submit

August 25, 2015

Conditions

Keywords

pudendal blockHypospadiascaudal blockchildanalgesia

Outcome Measures

Primary Outcomes (1)

  • postoperative pain intensity measure

    pain scores are recorded (postoperative within 24 hours) the investigators use CHEOPS pain scale for evaluation pain intensity. When pain score is 7 or higher than 7, pain treatment is evaluated as inadequate.

    24 hours

Secondary Outcomes (5)

  • time to to first use of analgesic

    24 hours

  • parental satisfaction

    24 hours

  • the incidence of side effects

    24 hours

  • intraoperative analgesic requirement

    intraoperative

  • postoperative total analgesic requirements

    24 hours

Study Arms (2)

pudendal block group

ACTIVE COMPARATOR

nerve stimulated pudendal nerve block performed under general anesthesia

Procedure: pudendal nerve block

Caudal block group

ACTIVE COMPARATOR

caudal block performed under general anesthesia

Procedure: caudal block

Interventions

nerve stimulator-guided Pudendal block

pudendal block group
caudal blockPROCEDURE

caudal block

Caudal block group

Eligibility Criteria

Age1 Year - 10 Years
Sexmale
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • ASA physical status I-II
  • aged 1 to 10 years scheduled undergoing hypospadias surgery

You may not qualify if:

  • history of allergic reactions to local anesthetics
  • rash or infection at the injection site
  • anatomical abnormality
  • bleeding diatheses, coagulopathy, liver diseases

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (2)

  • Naja ZM, Ziade FM, Kamel R, El-Kayali S, Daoud N, El-Rajab MA. The effectiveness of pudendal nerve block versus caudal block anesthesia for hypospadias in children. Anesth Analg. 2013 Dec;117(6):1401-7. doi: 10.1213/ANE.0b013e3182a8ee52.

    PMID: 24257391BACKGROUND
  • Kendigelen P, Tutuncu AC, Emre S, Altindas F, Kaya G. Pudendal Versus Caudal Block in Children Undergoing Hypospadias Surgery: A Randomized Controlled Trial. Reg Anesth Pain Med. 2016 Sep-Oct;41(5):610-5. doi: 10.1097/AAP.0000000000000447.

MeSH Terms

Conditions

PainHypospadiasAgnosia

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsUrogenital AbnormalitiesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesPenile DiseasesGenital Diseases, MaleGenital DiseasesMale Urogenital DiseasesCongenital AbnormalitiesCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesPerceptual DisordersNeurobehavioral ManifestationsNervous System Diseases

Study Officials

  • Guner Kaya, Prof.

    Istanbul University

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
M.D.(Anesthesiology Specialist)

Study Record Dates

First Submitted

January 26, 2015

First Posted

March 17, 2015

Study Start

November 1, 2014

Primary Completion

May 1, 2015

Study Completion

May 1, 2015

Last Updated

August 26, 2015

Record last verified: 2015-08