NCT02387320

Brief Summary

This randomized controlled trial (RCT) in newly-diagnosed breast cancer patients seeks to determine the effectiveness of a self-care toolkit on specific symptoms associated with surgery as compared to a standard care group.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable anxiety

Timeline
Completed

Started Jul 2014

Longer than P75 for not_applicable anxiety

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2014

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

November 17, 2014

Completed
4 months until next milestone

First Posted

Study publicly available on registry

March 13, 2015

Completed
1.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2017

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2017

Completed
Last Updated

May 12, 2016

Status Verified

May 1, 2016

Enrollment Period

2.6 years

First QC Date

November 17, 2014

Last Update Submit

May 10, 2016

Conditions

Keywords

AnxietyPainNauseaFatigueSleep DisturbanceBreast CancerSurgery

Outcome Measures

Primary Outcomes (1)

  • Change from preoperative in VAS General Anxiety at post-operative

    Anxiety is rated by the patient on a scale of 0 to 10, 0 being "not at all anxious" and 10 being "extremely anxious." This instrument will take up to 1 minute to complete.

    Pre-operative (30 minutes to 5 hours prior to surgery) , Post-operative (within 10 hours after surgery)

Secondary Outcomes (4)

  • Change from pre-operative DVPRS at post-operative

    Pre-operative (30 minutes to 5 hours prior to surgery) , Post-operative (within 10 hours after surgery)

  • Change from preoperative VAS Nausea at post- operative

    Pre-operative (30 minutes to 5 hours prior to surgery) , Post-operative (within 10 hours after surgery)

  • Change from baseline (PROMIS-57) Fatigue to pre-operative and follow-up 2 weeks post-operative

    Baseline, Pre-operative (30 minutes to 5 hours prior to surgery), follow-up 2 weeks post-operative

  • Change from baseline (PROMIS-57) Sleep Disturbance to pre-operative and follow-up 2 weeks post-operative

    Baseline, Pre-operative (30 minutes to 5 hours prior to surgery), Follow-up 2 weeks post-operative

Study Arms (2)

Self-Care Toolkit

EXPERIMENTAL

Women randomized to self-care toolkit group will receive a toolkit which includes a spiral-bound instruction manual, a section of the manual that can be used as a journal, a portable mp3 player with 8 audiofile tracks with guided meditations to reduce stress and anxiety, and two acupressure wristbands to help prevent nausea.

Other: Self-Care Toolkit

Standard Care

NO INTERVENTION

Women randomized to the standard care group will be informed that they will continue to receive standard of care as delivered by the SAMMC Oncology Department. The research team will inform women randomized to standard care that they will receive the self-care toolkit at their two week post-operative visit and will be able to use it subsequently if they choose to.

Interventions

The self-care toolkit was designed and created for individuals undergoing surgery and/or invasive medical procedures. It provides individuals with guided instruction to learn several evidence-informed mind-body skills (e.g., breathing, relaxation, meditation, guided imagery) and tools (e.g., acupressure wristbands, journal) in order to regulate their own physiologic and emotional reactions to stressful situations and to lessen symptoms associated with surgery (principally pain, anxiety, nausea, fatigue, sleep disturbance).

Self-Care Toolkit

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • + years of age
  • Women treated at SAMMC Oncology clinic or CRDAMC Oncology clinic for newly-diagnosed breast cancer for whom surgery (e.g., lumpectomy or mastectomy) is the initial treatment option

You may not qualify if:

  • Women receiving chemotherapy, radiation or hormone therapy as first line treatment for breast cancer (i.e., any of these treatment options prior to surgery)
  • Severe hearing-impairment (i.e., that would interfere with ability to hear the toolkit audiofiles)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Carl R. Darnall Army Medical Center

Fort Hood, Texas, 76544, United States

RECRUITING

San Antonio Military Medical Center

San Antonio, Texas, 78234, United States

RECRUITING

MeSH Terms

Conditions

Anxiety DisordersPainNauseaFatigueParasomniasBreast Neoplasms

Condition Hierarchy (Ancestors)

Mental DisordersNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsSigns and Symptoms, DigestiveSleep Wake DisordersNervous System DiseasesNeoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Kimberly McConnell, EdD

    Samueli Institute

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Kimberly McConnell, EdD

CONTACT

Erika Stoerkel, BS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 17, 2014

First Posted

March 13, 2015

Study Start

July 1, 2014

Primary Completion

February 1, 2017

Study Completion

February 1, 2017

Last Updated

May 12, 2016

Record last verified: 2016-05

Data Sharing

IPD Sharing
Will not share

Locations