NCT02384863

Brief Summary

The purpose of this study is to describe the characteristics, evaluation, management and outcomes of acute chest pain, and to provide opportunities for future initiatives to improve the emergency care for patients experiencing acute chest pain in China.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
18,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Oct 2014

Typical duration for all trials

Geographic Reach
1 country

7 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2014

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

February 26, 2015

Completed
12 days until next milestone

First Posted

Study publicly available on registry

March 10, 2015

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

March 10, 2015

Status Verified

March 1, 2015

Enrollment Period

2.2 years

First QC Date

February 26, 2015

Last Update Submit

March 9, 2015

Conditions

Chest PainAcute Coronary Syndrome

Keywords

Chest PainAcute Coronary SyndromeCardiacEmergency DepartmentCardiac TestingHealthcare UtilizationPatient Centered OutcomesShared Decision MakingUnnecessary hospital admissionsDecision Aid

Outcome Measures

Primary Outcomes (1)

  • in-hospital mortality

    During hospital stay,an expected average of 7 days

Secondary Outcomes (3)

  • Time between symptom onset and hospital admission

    Time interval from symptom onset to arrival at the Emergency Department，an expected median of 9 hours

  • Major adverse cardiac events (MACE)

    1 year

  • Cost-Effectiveness Analysis

    1 year

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

consecutive patients attending the emergency department in 7 Chinese grade Ⅲ hospitals

You may qualify if:

  • Acute chest pain(pain in the area inferior to the clavicle, superior to the rib arch, and anterior to the bilateral posterior axillary line）;
  • Possible Acute Coronary Syndrome;
  • Symptoms occurring within last 24 hours;
  • Informed consent from patient or next of kin.

You may not qualify if:

  • Arrhythmia or heart failure not cause by myocardial ischemia;
  • Confirmed lung disease without chest pain;
  • No onset of symptoms within last 24 hours;
  • No written consensus.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (7)

First Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, 150001, China

NOT YET RECRUITING

Henan Provincial Hospital

Zhengzhou, Henan, 450003, China

NOT YET RECRUITING

Second Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, 710004, China

NOT YET RECRUITING

Qilu Hospital of Shandong University

Jinan, Shandong, 250012, China

RECRUITING

Shanghai Chest Hospital

Shanghai, Shanghai Municipality, 200030, China

NOT YET RECRUITING

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, 200092, China

NOT YET RECRUITING

West China Hospital

Chengdu, Sichuan, 610041, China

NOT YET RECRUITING

MeSH Terms

Conditions

Chest PainAcute Coronary SyndromeEmergencies

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsMyocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesDisease AttributesPathologic Processes

Study Officials

  • Yuguo Chen, M.D., Ph.D.

    Qilu Hospital of Shandong University

    STUDY CHAIR

Central Study Contacts

Yuguo Chen, M.D., Ph.D.

CONTACT

86-18678812777chen919085@126.com

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
1 Year
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
President-elect, Chinese Society of Emergency Medicine;Director, Chest Pain Center, Qilu Hospital of Shandong University

Study Record Dates

First Submitted

February 26, 2015

First Posted

March 10, 2015

Study Start

October 1, 2014

Primary Completion

December 1, 2016

Study Completion

December 1, 2016

Last Updated

March 10, 2015

Record last verified: 2015-03

Locations

CN(7)