NCT02383186

Brief Summary

The purpose of this study is to determine whether a single layer dermally sutured wound results in superior outcomes to a layered closure.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2014

Typical duration for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 28, 2014

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

November 10, 2014

Completed
4 months until next milestone

First Posted

Study publicly available on registry

March 9, 2015

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2016

Completed
Last Updated

July 18, 2017

Status Verified

July 1, 2017

Enrollment Period

1.8 years

First QC Date

November 10, 2014

Last Update Submit

July 17, 2017

Conditions

Outcome Measures

Primary Outcomes (2)

  • Assessment of Scar on the Patient and Observer Scar Assessment Scale at 3 Months

    After surgical procedure, half of the subject's wound will be closed by single layer suturing, while the other half is closed by layered cutaneous closure. After 3 months, subjects will return to clinic for evaluation of the cosmesis of both types of closure techniques.

    3 months

  • Assessment of Scar on the Patient and Observer Scar Assessment Scale at 12 Months

    After surgical procedure, half of the subject's wound will be closed by single layer suturing, while the other half is closed by layered cutaneous closure. After 12 months, subjects will return to clinic for evaluation of the cosmesis of both types of closure techniques.

    12 months

Secondary Outcomes (2)

  • Measurement of Scar Width

    3 months and 12 months

  • Assessment of Complications

    3 months and 12 months

Study Arms (2)

Dermal Suturing Only Wound Closure

ACTIVE COMPARATOR

The side assigned to dermal suturing only will be closed with a single layer of deep absorbable sutures. The method will be buried vertical mattress or set-back suturing at the surgeons discretion.

Procedure: Dermal Suturing Only Wound ClosureProcedure: Layered Cutaneous Wound Closure

Layered Cutaneous Wound Closure

ACTIVE COMPARATOR

The side assigned to layered closure is closed with 5-0 fast acting gut.

Procedure: Dermal Suturing Only Wound ClosureProcedure: Layered Cutaneous Wound Closure

Interventions

The side assigned to dermal suturing only will be closed with a single layer of deep absorbable sutures. The method will be buried vertical mattress or set-back suturing at the surgeons discretion.

Dermal Suturing Only Wound ClosureLayered Cutaneous Wound Closure

The side assigned to layered closure is closed with 5-0 fast acting gut.

Dermal Suturing Only Wound ClosureLayered Cutaneous Wound Closure

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Able to give informed consent themselves
  • Patient scheduled for cutaneous surgical procedure with predicted linear closure
  • Willing to return for follow up visits

You may not qualify if:

  • Mentally handicapped
  • Incarceration
  • Pregnant Women
  • Wounds with predicted closure length less than 3 cm
  • Wounds unable to be fully closed via primary closure

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Links

Study Officials

  • Daniel Eisen, M.D.

    University of California, Davis

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 10, 2014

First Posted

March 9, 2015

Study Start

May 28, 2014

Primary Completion

April 1, 2016

Study Completion

April 1, 2016

Last Updated

July 18, 2017

Record last verified: 2017-07