Study Stopped
assay difficulties
The ADRB3 Receptor in Pregnancy
The ADRB3 Adrenergic Receptor - a Possible New Target for Controlling Pre-eclampsia and Hypertension in Pregnancy and Uterine Contractions in Non-pregnant and Pregnant Myometrium
1 other identifier
observational
80
1 country
1
Brief Summary
The primary overall objective of this study is to characterize the levels of and compare levels of the ADRB3 receptor in human non-pregnant myometrium, pregnant myometrium at different time points in pregnancy, in normal and dysfunctional labor and also to measure levels and expression of these receptors in placental arteries at different maturation statuses of placenta and in pre-eclampsia/hypertension
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Nov 2014
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 1, 2014
CompletedFirst Submitted
Initial submission to the registry
November 11, 2014
CompletedFirst Posted
Study publicly available on registry
March 6, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 1, 2029
May 17, 2023
May 1, 2023
14.1 years
November 11, 2014
May 15, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
characterization of the levels of the ADRB3 receptor in human pregnant myometrium
1 month
Study Arms (4)
Women with preeclampsia
Women delivered by cesarian section and with preeclampsia
Women with dysfunctional labor
Women delivered with cesarian section due to dtsfunctional labor
Women with cesarian section due to maternal request
Women with cesarian section due to maternal request
Women with preamture labor
Women with pemature labor undergoing cesarian section
Eligibility Criteria
Pregant women undergoing cesarian section.
You may qualify if:
- Women undergoing cesarian section
You may not qualify if:
- Interkurrent diseases
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Dept of Obstetrics and Gynecology, Danderyd Hospital
Stockholm, 18288, Sweden
Biospecimen
uterine specimen placental specimen
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD, PhD
Study Record Dates
First Submitted
November 11, 2014
First Posted
March 6, 2015
Study Start
November 1, 2014
Primary Completion (Estimated)
December 1, 2028
Study Completion (Estimated)
December 1, 2029
Last Updated
May 17, 2023
Record last verified: 2023-05