NCT02380261

Brief Summary

The purpose of this study is to verify the skin and ocular tolerance of the product Systane® Lid Wipes.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
35

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Sep 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 27, 2015

Completed
6 days until next milestone

First Posted

Study publicly available on registry

March 5, 2015

Completed
6 months until next milestone

Study Start

First participant enrolled

September 1, 2015

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2015

Completed
1.1 years until next milestone

Results Posted

Study results publicly available

November 18, 2016

Completed
Last Updated

November 18, 2016

Status Verified

August 1, 2016

Enrollment Period

1 month

First QC Date

February 27, 2015

Results QC Date

August 9, 2016

Last Update Submit

September 29, 2016

Conditions

Outcome Measures

Primary Outcomes (2)

  • Number of Participants With a Contact-dermatitis Adverse Reaction

    Participants were assessed by a dermatologist. Contact-dermatitis adverse reaction was characterized by the presence of one or more of the following symptoms or signs: strong itching sensation, erythema, edema, desquamation, papules or vesicles. Both eyes contributed to the analysis.

    Day 21

  • Number of Participants With Ocular Clinical Signs and Discomfort Sensations

    Participants were assessed by an ophthalmologist. Ocular clinical signs included palpebral edema, conjunctival edema, orbicular secretion, keratoconus, blepharitis, meibomitis, pterygium, hyperemia, chemosis, keratitis, secretion and lacrimation. Both eyes contributed to the analysis.

    Day 21

Study Arms (1)

Systane

EXPERIMENTAL

Systane® Lid Wipes, 1 per eyelid, used once and discarded after each use, for 21 days

Other: Systane® Lid Wipes

Interventions

Commercially-marketed, individually-packaged, pre-moistened eyelid wipe for daily cleaning

Systane

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Must sign informed consent.
  • Agree to adhere to the procedures and requirements of the study.
  • Wears makeup daily.

You may not qualify if:

  • Pregnant or breastfeeding.
  • Ocular conditions as specified in protocol.
  • Medical conditions as specified in protocol.
  • Skin conditions as specified in protocol.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Novartis Biociencias SA

São Paulo, 04636-000, Brazil

Location

Results Point of Contact

Title
Dir Clinical Operations - LACAR, GCRA
Organization
Alcon, a Novartis company

Study Officials

  • Medical Director

    Alcon Brazil

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
SINGLE
Who Masked
PARTICIPANT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 27, 2015

First Posted

March 5, 2015

Study Start

September 1, 2015

Primary Completion

October 1, 2015

Study Completion

October 1, 2015

Last Updated

November 18, 2016

Results First Posted

November 18, 2016

Record last verified: 2016-08

Locations