Juvenile Inflammatory Rheumatism (JIR) Cohorte
JIR-cohorte
Setting up a Pediatric Cohort for Inflammatory Rheumatic Diseases
1 other identifier
observational
15,000
5 countries
45
Brief Summary
The investigators created a cohort of patients with juvenile inflammatory rheumatisms with the purpose to follow them prospectively, and investigate the tolerance and efficacy of immunosuppresive and biological agents.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2014
Longer than P75 for all trials
45 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2014
CompletedFirst Submitted
Initial submission to the registry
October 9, 2014
CompletedFirst Posted
Study publicly available on registry
March 3, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
December 1, 2030
June 15, 2023
June 1, 2023
14.9 years
October 9, 2014
June 12, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Number of severe and very severe adverse event as a mesure of safety and tolerability
10 years
Number of treatments prescribed off label
10 Years
Length in months of drug survival in patient treated with at least two consecutive biological agents
10 Years
Study Arms (1)
Juvenile Inflammatory Rheumatism
Juvenile Inflammatory Rheumatism patients
Eligibility Criteria
All patients with juvenile inflammatory diseases
You may qualify if:
- Patients with juvenile inflammatory diseases
- Age at onset up to 18 years old
- Consent according national codes of ethics and current laws
You may not qualify if:
- Non-consent from patients and/or legal representative
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Michaël Hoferlead
- Hospices Civils de Lyoncollaborator
- Versailles Hospitalcollaborator
- Tenon Hospital, Pariscollaborator
- Bicetre Hospitalcollaborator
- University of Lausanne Hospitalscollaborator
- University Hospital Muenstercollaborator
- Fondation Rhumatismes-Enfants-Suissecollaborator
Study Sites (45)
Hôpital Reine Fabiola
Brussels, Belgium
CHU Charleroi
Charleroi, Belgium
UZ Leuven
Leuven, 3000, Belgium
CHC Liège
Liège, Belgium
CHR Citadelle
Liège, Belgium
CHU Belfort
Belfort, France
CHRU Besançon
Besançon, France
Hôpital Pellegrin enfants
Bordeaux, 33000, France
CHRU Brest
Brest, France
Hôpital Femme Mère Enfant
Bron, 69677, France
CHU Clermont-Ferrand
Clermont-Ferrand, 63003, France
CHU de Grenoble
Grenoble, France
Hôpital Bicêtre
Le Kremlin-Bicêtre, 94270, France
CHRU Lille
Lille, France
Hôpital Nord Marseille
Marseille, France
CHU Arnaud de Villeneuve
Montpellier, 34295, France
Centre hospitalier de Mulhouse
Mulhouse, 68100, France
CHU Nantes
Nantes, France
Nice CHU - Lenval
Nice, France
CHU Nimes
Nîmes, France
Hôpital necker Enfants Malade
Paris, France
Hôpital Robert Debré
Paris, France
Hôpital Tenon
Paris, France
CHU Reims
Reims, France
CHU Rennes
Rennes, France
CHU St-Etienne
Saint-Etienne, France
Hôpital de Hautepierre
Strasbourg, 67100, France
Hôpital des enfants
Toulouse, 31059, France
CHU Tours
Tours, France
Hôpital André Mignot
Versailles, 78157, France
University Hospital Muenster
Münster, Germany
Hôpital Ibnou Rochd
Casablanca, 20042, Morocco
CHUV
Lausanne, Canton of Vaud, 1011, Switzerland
Kantonsspital Aarau
Aarau, 5000, Switzerland
Kinderspital Basel
Basel, 4056, Switzerland
Universitäts-Augenklinik Basel
Basel, Switzerland
Ospedale Regionale di Bellinzona e valli
Bellinzona, Switzerland
Kantonspital Graubunden
Chur, 7000, Switzerland
Hôpital Ophtalmique
Lausanne, 1004, Switzerland
Kinderspital Luzern
Lucerne, 6000, Switzerland
Ospedale Regionale di Lugano
Lugano, Switzerland
Ostschweizer Kinderspital St-Gallen
Sankt Gallen, Switzerland
Klinik für Rheumatologie und internistische Rehabilitation
Valens, 7317, Switzerland
Kantonspital Winterthur
Winterthur, Switzerland
Kinderspital Zürich
Zurich, 8032, Switzerland
Related Publications (1)
Pouletty M, Borocco C, Ouldali N, Caseris M, Basmaci R, Lachaume N, Bensaid P, Pichard S, Kouider H, Morelle G, Craiu I, Pondarre C, Deho A, Maroni A, Oualha M, Amoura Z, Haroche J, Chommeloux J, Bajolle F, Beyler C, Bonacorsi S, Carcelain G, Kone-Paut I, Bader-Meunier B, Faye A, Meinzer U, Galeotti C, Melki I. Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort. Ann Rheum Dis. 2020 Aug;79(8):999-1006. doi: 10.1136/annrheumdis-2020-217960. Epub 2020 Jun 11.
PMID: 32527868DERIVED
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Michael Hofer
University of Lausanne Hospitals
- STUDY DIRECTOR
Véronique Hentgen
Versailles Hospital
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 10 Years
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Head of Pediatric Rheumatology unit
Study Record Dates
First Submitted
October 9, 2014
First Posted
March 3, 2015
Study Start
January 1, 2014
Primary Completion (Estimated)
December 1, 2028
Study Completion (Estimated)
December 1, 2030
Last Updated
June 15, 2023
Record last verified: 2023-06