NCT02376556

Brief Summary

The investigators aim to assess the effect of blepharoplasty with or without muller muscle resection on the symptoms of dry eye syndrome. this will be an observational study in which patients undergoing the aforementioned surgeries will be followed up and monitored for dry eye symptoms.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
54

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Mar 2015

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 25, 2015

Completed
4 days until next milestone

Study Start

First participant enrolled

March 1, 2015

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 3, 2015

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2018

Completed
Last Updated

October 15, 2019

Status Verified

October 1, 2019

Enrollment Period

3 years

First QC Date

February 25, 2015

Last Update Submit

October 11, 2019

Conditions

Keywords

Dry eye syndromeBlepharoplastyMuller muscle resection surgery

Outcome Measures

Primary Outcomes (1)

  • Objective assessment of dry eye syndrome

    3 months postoperatively

Secondary Outcomes (1)

  • Subjective assessment of dry eye syndrome

    3 months postoperatively

Study Arms (2)

Blepharoplasty

patients undergoing upper eyelid blepharoplasty

blepharoplasty and muller muscle resection

patients undergoing a combined blepharoplasty and muller muscle resection surgery

Eligibility Criteria

Age18 Years - 120 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients who are referred for blepharoplasty with or without muller muscle resection in the oculoplastic clinic in our institution

You may qualify if:

  • patients who are referred for blepharoplasty with or without muller muscle resection in the oculoplastic clinic in our institution
  • no other ophthalmic procedures planned for the patient in study period
  • ability to undergo full ophthalmic examination as stated in the study protocol
  • Ability to complete the dry eye questionnaire
  • ability to sign an informed consent form

You may not qualify if:

  • previous eyelid surgery
  • other orbital or lacrimal gland disease
  • concurrent use of contact lenses
  • concurrent use of Restasis
  • previous glaucoma surgery
  • use of punctual plugs
  • pregnant or nursing women

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sheba_Medical_Center

Ramat Gan, 52621, Israel

Location

MeSH Terms

Conditions

Dry Eye SyndromesBlepharoptosisCutis Laxa

Condition Hierarchy (Ancestors)

Lacrimal Apparatus DiseasesEye DiseasesEyelid DiseasesSkin Diseases, GeneticGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesConnective Tissue DiseasesSkin and Connective Tissue DiseasesSkin Diseases

Study Officials

  • Guy J Ben Simon, MD

    Sheba Medical Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Head, Orbital, Ophthalmic Plastic & Lacrimal Surgery department, The Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel

Study Record Dates

First Submitted

February 25, 2015

First Posted

March 3, 2015

Study Start

March 1, 2015

Primary Completion

March 1, 2018

Study Completion

March 1, 2018

Last Updated

October 15, 2019

Record last verified: 2019-10

Locations