NCT02373514

Brief Summary

Patients presented with dysmenorrhea composed the study population. One gram paracetamol and 50 mg dexketoprofen in 100 ml saline with a rapid infusion were compared in ceasing dysmenorrhea in emergency department.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for phase_4

Timeline
Completed

Started Jan 2015

Shorter than P25 for phase_4

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

February 23, 2015

Completed
4 days until next milestone

First Posted

Study publicly available on registry

February 27, 2015

Completed
2 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2015

Completed
Last Updated

February 27, 2015

Status Verified

February 1, 2015

Enrollment Period

2 months

First QC Date

February 23, 2015

Last Update Submit

February 26, 2015

Conditions

Outcome Measures

Primary Outcomes (2)

  • Visual Analogue Scale

    Change in visual analogue scale at 15th minutes from baseline

    15 minutes

  • Visual Analogue Scale

    Change in visual analogue scale at 30th minutes from baseline

    30 minutes

Secondary Outcomes (2)

  • Rescue drug need

    30 minutes

  • Adverse effects

    30 minutes

Study Arms (2)

Paracetamol

ACTIVE COMPARATOR

Intravenous 1 gm paracetamol in 100 ml saline with rapid infusion

Drug: Paracetamol

Dexketoprofen

ACTIVE COMPARATOR

Intravenous 50 mg dexketoprofen in 100 ml saline with rapid infusion

Drug: Dexketoprofen

Interventions

1 gr paracetamol in 100 ml saline with rapid infusion

Also known as: Perfalgan
Paracetamol

50 mg dexketoprofen in 100 ml saline with rapid infusion

Also known as: Arveles
Dexketoprofen

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with dysmenorrhea
  • Patients over 18 years old

You may not qualify if:

  • denied to give inform consent
  • Renal or liver failure
  • Allergy to the study drugs
  • Receiving pain killer within the last 6 hours.
  • Physical examination findings consistent with peritoneal irritation
  • Pregnancy or patients with lactation
  • Drug addiction

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pamukkale University

Denizli, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Dysmenorrhea

Interventions

Acetaminophendexketoprofen trometamol

Condition Hierarchy (Ancestors)

Menstruation DisturbancesPathologic ProcessesPathological Conditions, Signs and SymptomsPelvic PainPainNeurologic ManifestationsSigns and Symptoms

Intervention Hierarchy (Ancestors)

AcetanilidesAnilidesAmidesOrganic ChemicalsAniline CompoundsAmines

Study Officials

  • Mustafa Serinken, MD

    Pamukkale University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Cenker Eken, Medical Doctor

CONTACT

Mustafa Serinken, MD

CONTACT

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
QUADRUPLE
Who Masked
PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

February 23, 2015

First Posted

February 27, 2015

Study Start

January 1, 2015

Primary Completion

March 1, 2015

Study Completion

March 1, 2015

Last Updated

February 27, 2015

Record last verified: 2015-02

Locations