Clinical and Neuromechanical Predictors for the Evolution of Chronic Non-specific Low Back Pain

NCT02373345 | Completed

• 1 other identifier: UQTR-IRSST-2013-2016
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the present study is to determine the association between factors known to be associated with the development of chronic low back pain (psychological and biological) and the evolution of functional disability in individuals with a history of low back pain. To do so, 100 individuals with a history of nonspecific low back pain will be followed over a period of 18 months. During this time frame, participants will be evaluated three times in the laboratory (initial, at 6 months and at 18 months) to determine pain and tolerance thresholds, pain inhibition processes as well as neuromuscular activation. Moreover, these participants will be assessed every three months (initial, 3, 6, 9 12, 15 and 18 months) for functional disability and pain intensity levels of their low back pain as well as for psychological symptoms usually associated with the development of chronic low back pain. It is hypothesized that high psychological symptoms measured initially will be associated with high functional disability throughout the study .

Conditions

Low Back Pain

Keywords

psychological factors; functional disability; pain thresholds; tolerance thresholds; motor adaptations; natural course

Outcome Measures

Primary Outcomes (1)

• Change from baseline in disability (Roland-Morris Disability Questionnaire)

  Roland-Morris Disability Questionnaire

  baseline, 3 months, 6, months. 9 months, 12 months, 15 months, 18 months

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Individuals with a history of nonspecific low back pain

You may qualify if:

• To have experienced at least one episode of disabling (resulting in loss of work or modified tasks at work) nonspecific low back pain in the past three years.

You may not qualify if:

• Specific causes of low back pain, arthritic conditions, other chronic pain conditions

Sponsors & Collaborators

• Université du Québec à Trois-Rivières: lead
• Institut de Recherche Robert-Sauvé en Santé et en Sécurité du Travail: collaborator
• Chaire de recherche en chiropratique FRCQ: collaborator

Study Sites (1)

Université du Québec à Trois-Rivières

Trois-Rivières, Quebec, G9A 5H7, Canada

Location

MeSH Terms

Conditions

Low Back Pain

Condition Hierarchy (Ancestors)

Back Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Martin Descarreaux, DC, PhD

  Université du Québec à Trois-Rivières

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: DC, PhD

Study Record Dates

• First Submitted: February 21, 2015
• First Posted: February 27, 2015
• Study Start: February 1, 2013
• Primary Completion: December 1, 2015
• Study Completion: December 1, 2015
• Last Updated: May 17, 2016

Record last verified: 2016-05

Locations

CA (1)