"Study of Halitosis in Patients With Advanced Chronic Periodontitis"

NCT02368678 | Completed

• 1 other identifier: K4gnj9dd
• Study Type: interventional
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

The objective of this study was to evaluate whether short-term full mouth disinfection protocol could have a greater reduction in the levels of halitosis and volatile sulfur compound or not, when compared to quadrant-wise scaling and root planing

Conditions

Periodontal Disease; Halitosis; Periodontitis

Keywords

Halitosis; Sulfur compounds; Periodontitis; Periodontal treatment

Outcome Measures

Primary Outcomes (1)

• Change from baseline in Halitosis at 3 months

  Reduction in the number of patients with halitosis and improvement regarding halitosis severity

  Baseline and 90 days

Secondary Outcomes (1)

• Change from baseline in clinical attachment level at 3 months

  Baseline and 90 days

Study Arms (2)

Scaling and Root Planning (SRP)

ACTIVE COMPARATOR

Scaling and root planing (SRP) (n=15): the traditional mechanical periodontal therapy consisting of quadrant-wise (30 min. per quadrant) scaling and root planning performed at weekly sessions (one or two weeks of interval between session) and completed within 2 months.

Procedure: Scaling and Root Planning (SRP)

Full Mouth Scaling (FMS)

ACTIVE COMPARATOR

Full mouth scaling (FMS) (n=15): the alternative mechanical periodontal therapy consisting of full-mouth scaling and root planning completed in a single stage within 24 hours; i.e two sessions (60 min. per session) in two consecutive days.

Procedure: Full Mouth Scaling (FMS)

Interventions

Scaling and Root Planning (SRP) PROCEDURE

Scaling and Root Planing (n=15): quadrant-wise scaling and root planing performed within four weekly session (30 min. per quadrant). Oral malodor was measured by organoleptic test and Oral Chroma (Abilit, Osaka Japan) prior to the oral examination, at Baseline and also at 90 days after treatment. Clinical monitoring and tongue coating index were taken at these same times. Oral hygiene instructions were given to all participants.

Scaling and Root Planning (SRP)

Full Mouth Scaling (FMS) PROCEDURE

Full Mouth Scaling (n=15): scaling and root planning was performed in a single stage (within 24 hours); two sessions (60 min. per session) in two consecutive days. Oral malodor was measured by organoleptic test and Oral Chroma (Abilit, Osaka Japan) prior to the oral examination, at Baseline and also at 90 days after treatment. Clinical monitoring and tongue coating index were taken at these same times. Oral hygiene instructions were given to all participants.

Full Mouth Scaling (FMS)

Eligibility Criteria

• Age: 35 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• age between 35 and 60 years
• presence of at least 20 natural teeth
• diagnosis of chronic periodontitis
• halitosis
• no smokers

You may not qualify if:

• smokers or former smokers
• individuals diagnosed with diabetes and / or immunological disorders
• pregnant or lactating / patients with removable partial dentures and / or fixed or removable orthodontic appliance
• systemic use of antibiotics or anti-inflammatory in the last six months
• need for prophylactic use of antibiotics for performing the treatment
• regular use or use in the last six months of any kind of mouthwash
• individuals who underwent periodontal treatment in the 6 months preceding the start of the study

Sponsors & Collaborators

• Federal University of Minas Gerais: lead

Related Publications (54)

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MeSH Terms

Conditions

Periodontal Diseases; Halitosis; Periodontitis

Interventions

Tooth Exfoliation

Condition Hierarchy (Ancestors)

Mouth Diseases; Stomatognathic Diseases; Signs and Symptoms, Digestive; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Dental Physiological Phenomena; Digestive System and Oral Physiological Phenomena

Study Officials

• Juliana O. da Silveira, Master

  Federal University of Minas Gerais

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: CARE PROVIDER, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Juliana Oliveira da Silveira

Study Record Dates

• First Submitted: February 8, 2015
• First Posted: February 23, 2015
• Study Start: April 1, 2013
• Primary Completion: May 1, 2014
• Study Completion: May 1, 2014
• Last Updated: February 23, 2015

Record last verified: 2015-02