NCT02368639

Brief Summary

This study will use a modified version of a positive airway pressure device to supply air to the participant, while undergoing supervised polysomnography. Positive airway pressures are typically applied to many patients with hypoventilation, in this study these pressures will be titrated by a qualified sleep technician. During the night these pressures will be altered to optimise comfort.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
14

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jan 2015

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

February 8, 2015

Completed
15 days until next milestone

First Posted

Study publicly available on registry

February 23, 2015

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2016

Completed
Last Updated

August 11, 2017

Status Verified

August 1, 2017

Enrollment Period

1.2 years

First QC Date

February 8, 2015

Last Update Submit

August 9, 2017

Conditions

Outcome Measures

Primary Outcomes (2)

  • Apnea hypopnea index (AHI)

    The number of apnea and hypopneas will be measured

    8 hours

  • Peripheral blood oxygen level (SpO2)

    Peripheral blood oxygen level will be measured

    8 hours

Study Arms (1)

Positive airway pressure (PAP) device

EXPERIMENTAL

Fisher \& Paykel Healthcare PAP Device. Participants will sleep overnight using themodified positive airway pressure device. Their pressures will be titrated by a qualified sleep technician, they will then be optimised during the night.

Device: Fisher & Paykel Healthcare PAP Device

Interventions

The device is a modified version of the Fisher \& Paykel Icon continuous positive airway pressure (CPAP) device, which is a fully released product in New Zealand.

Positive airway pressure (PAP) device

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Aged 18+
  • Patients diagnosed with obesity hypoventilation syndrome (OHS) and/or obstructive sleep apnea (OSA) by a practicing sleep or respiratory physician, requiring positive airway pressure (PAP) therapy

You may not qualify if:

  • Recent cardiac or respiratory arrest
  • Gastro intestinal bleeding, ileus or recent gastrointestinal surgery
  • Coma, decreased level of consciousness or agitation
  • Anatomical or subjective difficulty with airway access e.g. facial surgery, trauma, vomiting upper airway obstruction
  • Cerebrospinal fluid leak, abnormalities of the cribiform plate or prior history of head trauma.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fisher & Paykel Healthcare Sleep Laboratory

Auckland, New Zealand

Location

MeSH Terms

Conditions

Sleep Apnea, ObstructiveObesity Hypoventilation Syndrome

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesHypoventilationRespiratory InsufficiencyObesityOverweightOvernutritionNutrition DisordersNutritional and Metabolic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 8, 2015

First Posted

February 23, 2015

Study Start

January 1, 2015

Primary Completion

March 1, 2016

Study Completion

March 1, 2016

Last Updated

August 11, 2017

Record last verified: 2017-08

Locations