NCT02364375

Brief Summary

The primary objective of this study is to evaluate the subjective performance of the Menai mask systems (full face, nasal, and pillows variants), compared against Comparison mask systems.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started May 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 1, 2015

Completed
17 days until next milestone

First Posted

Study publicly available on registry

February 18, 2015

Completed
2 months until next milestone

Study Start

First participant enrolled

May 1, 2015

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2015

Completed
Last Updated

February 4, 2021

Status Verified

February 1, 2021

Enrollment Period

2 months

First QC Date

February 1, 2015

Last Update Submit

February 2, 2021

Conditions

Keywords

sleepapneaOSACPAP

Outcome Measures

Primary Outcomes (1)

  • Usability Performance Evaluation

    Evaluation of the usability performance (seal, comfort, etc) of the Menai masks, compared to the Comparison Menai Standard masks.

    2 weeks

Secondary Outcomes (1)

  • Humidification Performance Evaluation

    2 weeks

Study Arms (3)

Full Face

EXPERIMENTAL

Participants will trial the same mask type/variant (full face, nasal, pillows) as the variant they are using as part of their current treatment. Participants in this arm will trial the Menai mask (full face) and Comparison Menai Standard mask (full face) for 7 nights each.

Device: Menai mask (full face)Device: Menai Standard mask (full face)

Nasal

EXPERIMENTAL

Participants will trial the same mask type/variant (full face, nasal, pillows) as the variant they are using as part of their current treatment. Participants in this arm will trial the Menai mask (nasal) and Comparison Menai Standard mask (nasal) for 7 nights each.

Device: Menai mask (nasal)Device: Menai Standard mask (nasal)

Pillows

EXPERIMENTAL

Participants will trial the same mask type/variant (full face, nasal, pillows) as the variant they are using as part of their current treatment. Participants in this arm will trial the Menai mask (pillows) and Comparison Menai Standard mask (pillows) for 7 nights each.

Device: Menai mask (pillows)Device: Menai Standard mask (pillows)

Interventions

Prototype mask system (full face variant) with novel vent and humidification system

Full Face

Prototype mask system (full face variant) with conventional vent and humidification system

Full Face

Prototype mask system (nasal variant) with novel vent and humidification system

Nasal

Prototype mask system (nasal variant) with conventional vent and humidification system

Nasal

Prototype mask system (pillows variant) with conventional vent and humidification system

Pillows

Prototype mask system (pillows variant) with conventional vent and humidification system

Pillows

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Participants willing to provide written informed consent
  • Participants who can read and comprehend written and spoken English
  • Participants who are over 18 years of age
  • Participants who have been diagnosed with OSA
  • Participants who have been established on CPAP for ≥ 6 months
  • Participants who are currently using the same mask type/variant as the interventional mask system to be evaluated

You may not qualify if:

  • Participants who are not able to provide written informed consent
  • Participants who are unable to comprehend written and spoken English
  • Participants who are pregnant
  • Participants who are unsuitable to participate in the study in the opinion of the researcher
  • Participants with a pre-existing lung disease or a condition that would predispose them to pneumothorax (e.g. COPD, lung cancer; fibrosis of the lungs; recent (\< 2years) case of pneumonia or lung infection, lung injury)
  • Participants who cannot participate for the duration of the trial
  • Participants who are established on bi-level support therapy
  • Participants who are not currently using the same mask type/variant as the interventional mask system to be evaluated

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

ResMed Sleep Research Centre

Sydney, New South Wales, 2153, Australia

Location

MeSH Terms

Conditions

Sleep Apnea, ObstructiveApnea

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesSigns and Symptoms, RespiratorySigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Klaus Schindhelm, BE PhD

    Graduate School of Biomedical Engineering, University of New South Wales, Sydney Australia and Applied Research, ResMed Ltd Sydney Australia

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 1, 2015

First Posted

February 18, 2015

Study Start

May 1, 2015

Primary Completion

July 1, 2015

Study Completion

July 1, 2015

Last Updated

February 4, 2021

Record last verified: 2021-02

Locations