Maximal Inspiratory Pressure at Extubation: Relationship With Mortality
1 other identifier
observational
124
1 country
1
Brief Summary
The process of weaning from mechanical ventilation was decided after clinical judgment and weaning predictive index. Nevertheless, indexes predicting weaning outcome like Maximal Inspiratory Pressure (MIP) are frequently inaccurate. However the long-term involvement of respiratory muscles in critically ill patients has not been established. The objective of this study was to assess the relationship on MIP at extubation on one-year mortality in critically ill patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2014
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2014
CompletedFirst Submitted
Initial submission to the registry
February 9, 2015
CompletedFirst Posted
Study publicly available on registry
February 13, 2015
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2016
CompletedJanuary 12, 2016
January 1, 2016
2 years
February 9, 2015
January 8, 2016
Conditions
Outcome Measures
Primary Outcomes (1)
Mortality
One year after extubation
Secondary Outcomes (1)
Time to mechanical ventilation weaning
During Intensive care unit hospitalization
Study Arms (1)
patients under mechanical ventilation
Eligibility Criteria
Critically ill patient under invasive mechanical ventilation
You may qualify if:
- Mechanical ventilation at least at 24 hours
You may not qualify if:
- Delirium
- Cognitive dysfunction
- refusal to participate
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Le Havre, Jacques Monod Hospital
Montivilliers, 76290, France
Related Publications (3)
Combret Y, Prieur G, Hilfiker R, Gravier FE, Smondack P, Contal O, Lamia B, Bonnevie T, Medrinal C. The relationship between maximal expiratory pressure values and critical outcomes in mechanically ventilated patients: a post hoc analysis of an observational study. Ann Intensive Care. 2021 Jan 13;11(1):8. doi: 10.1186/s13613-020-00791-4.
PMID: 33438092DERIVEDMedrinal C, Prieur G, Combret Y, Quesada AR, Bonnevie T, Gravier FE, Frenoy E, Contal O, Lamia B. Reliability of respiratory pressure measurements in ventilated and non-ventilated patients in ICU: an observational study. Ann Intensive Care. 2018 Jan 30;8(1):14. doi: 10.1186/s13613-018-0362-1.
PMID: 29380080DERIVEDMedrinal C, Prieur G, Frenoy E, Robledo Quesada A, Poncet A, Bonnevie T, Gravier FE, Lamia B, Contal O. Respiratory weakness after mechanical ventilation is associated with one-year mortality - a prospective study. Crit Care. 2016 Jul 31;20(1):231. doi: 10.1186/s13054-016-1418-y.
PMID: 27475524DERIVED
Study Officials
- PRINCIPAL INVESTIGATOR
Clement Medrinal
Groupe Hospitalier du Havre
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- MD, PhD
Study Record Dates
First Submitted
February 9, 2015
First Posted
February 13, 2015
Study Start
January 1, 2014
Primary Completion
January 1, 2016
Study Completion
January 1, 2016
Last Updated
January 12, 2016
Record last verified: 2016-01