NCT02357329

Brief Summary

This study will investigate fat taste and if free fatty acids (FFA) in food function as a signal for fat content. FFA are quite unpleasant - the investigators want to measure if the concentration in different foods correlates with hedonic preference. FFA concentration from a variety of foods will be used to determine if people who have greater sensitivity for FFA find foods with higher FFA concentrations less acceptable. Further, this study with determine whether the relationship between fat taste and hedonic food preference is modified by sex and body mass index (BMI).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
52

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Oct 2014

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2014

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2014

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

December 22, 2014

Completed
2 months until next milestone

First Posted

Study publicly available on registry

February 6, 2015

Completed
Last Updated

February 6, 2015

Status Verified

December 1, 2014

Enrollment Period

1 month

First QC Date

December 22, 2014

Last Update Submit

February 2, 2015

Conditions

Fat Taste

Keywords

fat tastefood preferenceconsumptionfree fatty acids

Outcome Measures

Primary Outcomes (1)

  • NEFA sensitivity (Participants will taste and rate 10 solutions based on intensity)

    Participants will taste and rate 10 solutions based on intensity

    1 day

Secondary Outcomes (1)

  • Food consumption and preference (Participants will answer questions regarding consumption of foods and preference)

    1 day

Study Arms (1)

Taste and hedonic ratings of NEFA

Linoleic acid solutions from 0.005% to 1.58%. Participants swish and spit 10 - 7.5mL solutions.

Eligibility Criteria

Age18 Years - 64 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

unselected convenience sample

You may qualify if:

  • Age 18-64
  • Healthy
  • Non-smoker

You may not qualify if:

  • Food allergies
  • Inability to detect and identify basic tastes

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Purdue Univeristy

West Lafayette, Indiana, 47907, United States

Location

MeSH Terms

Conditions

Food Preferences

Condition Hierarchy (Ancestors)

Feeding BehaviorBehavior

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Distinguished Prof. Nutrition Sciences

Study Record Dates

First Submitted

December 22, 2014

First Posted

February 6, 2015

Study Start

October 1, 2014

Primary Completion

November 1, 2014

Study Completion

November 1, 2014

Last Updated

February 6, 2015

Record last verified: 2014-12

Locations

US(1)