NCT02350374

Brief Summary

The total amount of carbohydrates (CHO) at meal consumed strongly predicts the glycemic response in children and adolescents with type 1 diabetes. Carbohydrate counting is a technique to adapt a dose of rapid acting insulin to the carbohydrate content of a meal. Thanks to this flexible insuline therapy, the glycemic control and the quality of life tend to improve. Carbohydrate counting is a recommended technique in the adult diabetic population. There is little data on the use of this methode in youth with diabetes. There are no studies on the change of carbohydrates content at meals in children and adolescents with diabetes practicing counting carbs, while it is the main interest of this technique. The aim of this study is to assess how children and adolescents with type 1 diabetes use the possibility to change their carbohydrate amount at each main meal when they use the counting carb method. The investigators hypothesize that children vary their amount of CHO greatly. This is an argument for using this technique in pediatrics

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
82

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Nov 2014

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 17, 2014

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

January 16, 2015

Completed
13 days until next milestone

First Posted

Study publicly available on registry

January 29, 2015

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 17, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 17, 2016

Completed
Last Updated

July 30, 2018

Status Verified

July 1, 2018

Enrollment Period

1.5 years

First QC Date

January 16, 2015

Last Update Submit

July 27, 2018

Conditions

Keywords

diabeteschildren

Outcome Measures

Primary Outcomes (1)

  • The individual variation of CHO amount at each main meal : Breakfast, Lunch, Snacks, Dinner

    the patients must fill their logbook during 28 days

    each day during 28 days

Study Arms (1)

carbohydrate counting

OTHER

patients must fill their logbook during 28 days

Other: carbohydrate counting

Interventions

patients must fill their logbook with the following data: * cho amount at breakfast, lunch, snack and dinner * insulin amount at breakfast, lunch, snack and dinner

carbohydrate counting

Eligibility Criteria

Age1 Year - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Treated for type 1 diabetes with a basal bolus regimen and practicing counting carbohydrates for nine months or more
  • With autoantibodies positive (anti-gad, anti-ia2, anti-islets ) or HLA typing predisposing to type 1 diabetes
  • Aged 1 to 18 years
  • affiliation to a social security scheme

You may not qualify if:

  • Aged less than 1 or more than 18 years
  • Autoantibody negative and HLA does not predispose to type 1 diabetes
  • No affiliation to a social security scheme

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fondation Lenval

Nice, 06200, France

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 1Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Marie HOFLACK, PhD

    Fondation Lenval

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 16, 2015

First Posted

January 29, 2015

Study Start

November 17, 2014

Primary Completion

May 17, 2016

Study Completion

May 17, 2016

Last Updated

July 30, 2018

Record last verified: 2018-07

Locations