Cushing´s Disease Epidemiology in Sweden

NCT02350153 | Completed

• 1 other identifier: NSSCDIO
• Study Type: observational
• Target: 502
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to study since 1987 all patients diagnosed with CD in Sweden and determine their outcomes including mortality. A secondary objective is to focus on patients in remission and identify determinants of their different outcomes.

Conditions

Cushing Disease

Keywords

Mortality; Morbidity; Incidence; Prevalence

Outcome Measures

Primary Outcomes (1)

• Mortality

  If event (death) has been occured during the observation period. Data obtained by the Swedish Cause Of Death Register (Swedish Board of Health and Welfare)

  From date of diagnosis until the last day of December 2014 or date of death from any cause, whichever came first, assessed up to 20 years.

Secondary Outcomes (6)

• influence of Cushing's Disease on myocardial infarction

  From date of diagnosis until the last day of December 2014 or date of death from any cause, whichever came first, assessed up to 20 years

• influence of Cushing's Disease on stroke

  From date of diagnosis until the last day of December 2014 or date of death from any cause, whichever came first, assessed up to 20 years

• influence of Cushing's Disease on cancer

  From date of diagnosis until the last day of December 2014 or date of death from any cause, whichever came first, assessed up to 20 years

• influence of Cushing's Disease on hip fracture risk

  From date of diagnosis until the last day of December 2014 or date of death from any cause, whichever came first, assessed up to 20 years

• incidence of Cushing's Disease in Sweden

  Assessed up to 20 years.

Study Arms (1)

Patients with verified Cushing's Disease

Patients with verified Cushing's Disease

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All adult patients with confirmed CD diagnosis in Sweden

You may qualify if:

• All patients registered with Cushing's Disease in Sweden since 1987 in the statistical database for in- and out-patients, at the Swedish National Board of Health and Welfare will be included in the study.

Sponsors & Collaborators

• Vastra Gotaland Region: lead

Study Sites (1)

Sahlgrenska University Hospital

Gothenburg, Västra Götaland County, 413 45, Sweden

Location

MeSH Terms

Conditions

Pituitary ACTH Hypersecretion

Condition Hierarchy (Ancestors)

Hyperpituitarism; Pituitary Diseases; Hypothalamic Diseases; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Endocrine System Diseases

Study Officials

• Gudmundur Johannsson, Professor

  Vastra Gotaland Region, Sahlgrenska University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 5, 2014
• First Posted: January 29, 2015
• Study Start: September 1, 2013
• Primary Completion: April 1, 2019
• Study Completion: April 1, 2019
• Last Updated: May 3, 2019

Record last verified: 2019-04

Locations

SE (1)