NCT02343770

Brief Summary

Juvenile idiopathic arthritis (JIA) is the most common form of arthritis in children. The etiology is unknown. Several types of arthritis fall under the JIA heading. Oligoarticular JIA with antinuclear antibodies affects about half of all children. There 's no specific markers. Our purpose is to identify new markers in this pathology. The ProtoArray®Human Protein Microarray allows rapid and efficient detection of protein interaction using a suitable protein or small molecule probe. The investigators hope so detect novel potential autoantigen biomarkers specific in JIA.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2015

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 7, 2015

Completed
15 days until next milestone

First Posted

Study publicly available on registry

January 22, 2015

Completed
4 months until next milestone

Study Start

First participant enrolled

June 1, 2015

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2015

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2016

Completed
Last Updated

September 7, 2015

Status Verified

September 1, 2015

Enrollment Period

6 months

First QC Date

January 7, 2015

Last Update Submit

September 4, 2015

Conditions

Idiopathic Juvenile Arthritis

Outcome Measures

Primary Outcomes (1)

  • identification of specific autoantigen biomarkers

    Identify blood sampling biomarkers of juvenile idiopathic arthritis

    1 day

Study Arms (2)

idiopathic juvenile arthritis

EXPERIMENTAL

blood sample

Other: blood sample for identifying biomarkers

control

OTHER

blood sample

Other: blood sample for identifying biomarkers

Interventions

blood sample for identifying biomarkersOTHER
controlidiopathic juvenile arthritis

Eligibility Criteria

Age2 Years - 16 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • child age from 2 to 16 years
  • Oligoarticular JIA with antinuclear antibodies
  • with or without uveitis

You may not qualify if:

  • immunosuppressive and biological therapy
  • child age from 2 to 16 years

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cardiology paediatric consultation, Arnaud de Villeneuve Hospital

Montpellier, 34295, France

RECRUITING

MeSH Terms

Conditions

Arthritis, Juvenile

Interventions

Blood Specimen Collection

Condition Hierarchy (Ancestors)

ArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Intervention Hierarchy (Ancestors)

Specimen HandlingClinical Laboratory TechniquesDiagnostic Techniques and ProceduresDiagnosisPuncturesSurgical Procedures, OperativeInvestigative Techniques

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 7, 2015

First Posted

January 22, 2015

Study Start

June 1, 2015

Primary Completion

December 1, 2015

Study Completion

December 1, 2016

Last Updated

September 7, 2015

Record last verified: 2015-09

Locations

FR(1)