Advanced MRI Sequences for Radiation Therapy Treatment Planning

NCT02340715 | Completed Results

• 1 other identifier: Advanced MRI
• Study Type: observational
• Target: 158
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to determine if it would be helpful to use advanced MRI imaging techniques to take additional views of the tumor target for radiation treatment planning or treatment follow-up MRI.

Conditions

Cancer

Keywords

Anal canal; Brain; Breast; Cervix; Esophagus; Gynecology; Head and Neck; Lung; Pancreas; Primary liver or liver metastases; Prostate cancer; Sarcoma

Outcome Measures

Primary Outcomes (1)

• Number of Participants Successfully Contributing MRI Data

  We tested these Advanced MR protocols to evaluate which ones would best visualize the target region. This helped us determine the optimum MR SIM protocols for different sites that became clinical standard.

  up to 4 weeks from imaging

Study Arms (1)

MRI for treatment planning or follow up

MRI for treatment planning for radiation therapy or those who have completed treatment and are receiving follow up care.

Eligibility Criteria

• Age: 18 Years - 89 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Subjects who are planning to have radiation therapy for their cancer.

You may qualify if:

• Patients aged 18 years older of any race or gender with anal canal, brain, breast, cervix, esophagus, gynecology, head and neck, lung, pancreas, primary liver or liver metastases, prostate cancer or sarcoma either undergoing MRI scan for radiation treatment planning or a post treatment MRI
• Voluntarily signs an IRB approved consent form

You may not qualify if:

• Inability to obtain informed consent from the patient or their medical power of attorney
• Patients who are not undergoing MR for radiation treatment planning
• Patients who will not have MRI scans after treatment
• Patients with pacemakers or other non-MRI compatible metallic implants
• Pregnant women, by self report using a standard MRI questionnaire
• Patients who will not receive contrast agent as part of their standard MR, will participate only in the non-contrast portion of the study

Sponsors & Collaborators

• Medical College of Wisconsin: lead

Study Sites (1)

Froedtert Hospital

Milwaukee, Wisconsin, 53226, United States

Location

Related Publications (1)

• Khoo VS, Dearnaley DP, Finnigan DJ, Padhani A, Tanner SF, Leach MO. Magnetic resonance imaging (MRI): considerations and applications in radiotherapy treatment planning. Radiother Oncol. 1997 Jan;42(1):1-15. doi: 10.1016/s0167-8140(96)01866-x.

  PMID: 9132820 BACKGROUND

MeSH Terms

Conditions

Neoplasms; Prostatic Neoplasms; Sarcoma

Condition Hierarchy (Ancestors)

Genital Neoplasms, Male; Urogenital Neoplasms; Neoplasms by Site; Genital Diseases, Male; Genital Diseases; Urogenital Diseases; Prostatic Diseases; Male Urogenital Diseases; Neoplasms, Connective and Soft Tissue; Neoplasms by Histologic Type

Results Point of Contact

• Title: Ergun Ahunbay
• Organization: Medical College of Wisconsin

eahunbay@mcw.edu

4148057898

Study Officials

• Ergun Ahunbay, PhD

  Medical College of Wisconsin

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: Yes

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Chief of Physics

Study Record Dates

• First Submitted: September 10, 2014
• First Posted: January 19, 2015
• Study Start: February 1, 2009
• Primary Completion: June 1, 2015
• Study Completion: June 1, 2015
• Last Updated: October 31, 2017
• Results First Posted: October 31, 2017

Record last verified: 2017-10

Locations

US (1)