Validation of Modified Early Warning Score (MEWS) in Predicting Outcomes in Clinical Oncology Ward Adult Patients

NCT02336828 | Unknown

• 1 other identifier: 1155044283
• Study Type: observational
• Target: 171
• Locations: 1 country
• Sites: 1

Brief Summary

This study is to validate the use of the modified early warning score (MEWS) in an adult oncology ward as a predictor of 7 day mortality or intensive care unit (ICU) admission. It is expected that either a MEWS score ≥4 or a change in score of ≥2 from the initial reading will be associated with an increased risk of death or ICU admission, and should be regarded as a MEWS Alarm. If MEWS is proof to be a reliable alternative tool, early diagnosis and aggressive management of life-threatening complications in oncology patients, results in dramatic improvements in overall survival rates. This is a prospective, single centre, observational, cohort study. Objective of this study is to investigate the ability of the Modified Early Warning Score (MEWS) to predict 7 day mortality in adult clinical oncology ward patients. The alternate hypothesis of this study is a significant difference in 7 day mortality between adult oncology ward patients with a MEWS Alarm and adult oncology ward patients without a MEWS alarm. The null hypothesis is a no significant difference in 7 day mortality between adult oncology ward patients with a MEWS Alarm and adult oncology ward patients without a MEWS alarm. The primary outcome measure in this study is the number of patients who die within 7 days of a MEWS Alarm (7 day mortality). The secondary outcome measure in this study is the number of patients admitted to ICU within 7 days of a MEWS Alarm.

Conditions

Oncologic Complications and Emergencies; Cancer; Emergencies

Keywords

MEWS; deteriorate; oncology; ICU; predicting outcomes; MEWS in predicting outcomes in oncology patients

Outcome Measures

Primary Outcomes (1)

• The number of patients who die within 7 days of a MEWS Alarm (7 day mortality).

  The 7 day mortality was counted from the on set of reaching the MEWS Alarm

Secondary Outcomes (1)

• The number of patients admitted to ICU within 7 days of a MEWS Alarm.

  The 7 day ICU admission was counted from the on set of reaching the MEWS Alarm

Study Arms (1)

MEWS alarm and mortality

Reach MEWS Alarm, Not reach MEWS Alarm, With 7 day mortality, Without 7 day mortality

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Clinical oncology ward adult patients

You may qualify if:

• The patients consecutively admitted to clinical oncology ward from 18 January to 7 February 2015 are included in the study.

You may not qualify if:

• The patients with incomplete MEWS or discharge data are excluded.

Sponsors & Collaborators

• Chinese University of Hong Kong: lead

Study Sites (1)

Queen Mary Hospital

Hong Kong, Hong Kong, China

RECRUITING

MeSH Terms

Conditions

Emergencies; Neoplasms

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• AU HANG CHING

  Chinese University of Hong Kong

  PRINCIPAL INVESTIGATOR

Central Study Contacts

AU HANG CHING

CONTACT

(+852)64060129; au1119@yahoo.com.hk

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Master Student

Study Record Dates

• First Submitted: January 8, 2015
• First Posted: January 13, 2015
• Study Start: January 1, 2015
• Primary Completion: February 1, 2015
• Study Completion: March 1, 2015
• Last Updated: January 26, 2015

Record last verified: 2015-01

Locations

CN (1)