NCT02335385

Brief Summary

Conventional laparoscopic varicocelectomy using 3 ports has been used for treatment of varicocele in our department since the nineties. However, the relatively several trocar wounds represent a big challenge against its acceptance by many of our patients who prefer the open approach with one or at least two wounds. Single incision laparoscopic surgery (SILS), since its introduction in 2007, has been proven to be feasible and effective, with high patient satisfaction rates regarding improved cosmotic outcomes, reduced postoperative pain, and rapid return to normal activities. (10, 11) SILS for varicocelectomy has been reported to be safe and effective alternative to conventional laparoscopic varicocelectomy in a few studies.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
90

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jun 2009

Typical duration for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2009

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2012

Completed
2.6 years until next milestone

First Submitted

Initial submission to the registry

January 7, 2015

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 9, 2015

Completed
Last Updated

January 9, 2015

Status Verified

January 1, 2015

Enrollment Period

3 years

First QC Date

January 7, 2015

Last Update Submit

January 7, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • number of patients with improvement in semen parameters and resolution of testicular pain

    2 years

Secondary Outcomes (1)

  • number of patients developing postoperative complications

    2 years

Study Arms (2)

SIL-V

ACTIVE COMPARATOR

single incision laparoscopic varicocelectomy

Procedure: single incision laparoscopic varicocelectomy

CTL-V

ACTIVE COMPARATOR

conventional transperitoneal laparoscopic varicocelectomy

Procedure: conventional transperitoneal laparoscopic varicocelectomy

Interventions

bilateral and unilateral varicocelectomy was performed through a single transumbilical flexible SILS port.

SIL-V

bilateral and unilateral varicocelectomy was performed through a conventional 3-ports transperitoneal varicoceletomy

CTL-V

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients with palpable varicoceles

You may not qualify if:

  • unfit for anesthesia or laparoscopy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Youssef T, Abdalla E. Single incision transumbilical laparoscopic varicocelectomy versus the conventional laparoscopic technique: A randomized clinical study. Int J Surg. 2015 Jun;18:178-83. doi: 10.1016/j.ijsu.2015.04.048. Epub 2015 May 1.

MeSH Terms

Conditions

Varicocele

Condition Hierarchy (Ancestors)

Genital Diseases, MaleGenital DiseasesUrogenital DiseasesMale Urogenital DiseasesVascular DiseasesCardiovascular Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
assistant professor of surgery

Study Record Dates

First Submitted

January 7, 2015

First Posted

January 9, 2015

Study Start

June 1, 2009

Primary Completion

June 1, 2012

Study Completion

June 1, 2012

Last Updated

January 9, 2015

Record last verified: 2015-01