NCT02333968

Brief Summary

Pain is a prevalent and distressing symptom in patients with cancer, having an enormous impact on functioning and quality of life. Integration of patient self-management and professional care by means of care technology provides new opportunities in the outpatient setting. In this project a technology based and nurse delivered multicomponent self-management support intervention has been developed. Important components include monitoring, feedback, education, and nurse support. Following feasibility evaluation, the primary aim of this randomized controlled trial is to assess the effect of the intervention regarding pain intensity and quality of life as compared to care as usual. Secondary outcomes of the effect evaluation are self-efficacy, knowledge, anxiety and depression, and pain medication use. Besides, a cost-evaluation and summative process evaluation will be performed.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
174

participants targeted

Target at P75+ for not_applicable pain

Timeline
Completed

Started Feb 2014

Typical duration for not_applicable pain

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2014

Completed
11 months until next milestone

First Submitted

Initial submission to the registry

December 29, 2014

Completed
10 days until next milestone

First Posted

Study publicly available on registry

January 8, 2015

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2015

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2015

Completed
Last Updated

January 8, 2015

Status Verified

January 1, 2015

Enrollment Period

1.3 years

First QC Date

December 29, 2014

Last Update Submit

January 7, 2015

Conditions

Keywords

Cancer painSelf-managementRandomized controlled trial

Outcome Measures

Primary Outcomes (2)

  • Change in pain intensity (Brief Pain Inventory - Short Form (BPI-SF)

    As measured with the Brief Pain Inventory - Short Form (BPI-SF)

    12 weeks

  • Change in cancer related quality of life (European Organisation for Research and Treatment of Cancer Quality of life Questionnaire (EORTC QLQ-C30 version 3)

    As measured with the European Organisation for Research and Treatment of Cancer Quality of life Questionnaire (EORTC QLQ-C30 version 3)

    12 weeks

Secondary Outcomes (4)

  • Change in self-efficacy (Chronic Pain Self-efficacy Scale (CPSS)

    12 weeks

  • Change in knowledge about cancer pain (Pain Knowledge Questionnaire (PKQ)

    12 weeks

  • Change in anxiety and depression (Hospital Anxiety and Depression Scale (HADS)

    12 weeks

  • Change in pain medication use (Brief Pain Inventory - Short Form (BPI-SF), a cost diary and a pharmacist's overview)

    12 weeks

Study Arms (2)

Intervention group

EXPERIMENTAL

Self-management support

Behavioral: Self-management support

Control group

NO INTERVENTION

Care as usual

Interventions

The 12-week intervention consists of an iPad application for patients that is connected to a web application for nurses. Every morning and evening patients register pain and related symptoms by use of a pain diary. Patients are also requested to register medication intake. Graphical feedback is provided based on registered pain scores and medication intakes. Patients receive education on causes and treatment of pain, symptoms that require action, and methods to better control pain. Patients communicate with nurses via text message functionality within the application. Specialized nurses remotely monitor and analyze the patients' situation once every workday. Nurses have the opportunity to collaborate with the treating physician, pain specialist or multidisciplinary team.

Intervention group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of cancer
  • Patients who are under (palliative) anti-tumour treatment in a day clinic or outpatient clinic, or patients who have no treatment options available anymore
  • Cancer (treatment related) pain \> 2 weeks
  • Pain is defined as a patient reported pain score of 4 or more on a numerical rating scale (scale 0-10)
  • Living at home

You may not qualify if:

  • Expected life expectancy \< 3 months
  • Chronic non-cancer pain
  • Known cognitive impairments
  • Participation in other studies that interfere with this study
  • Not being able to read and understand the Dutch language
  • Reduced vision
  • Non-reachable by phone

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Atrium Medical Center

Heerlen, Netherlands

RECRUITING

Maastricht University Medical Center

Maastricht, Netherlands

RECRUITING

Related Publications (1)

  • Hochstenbach LM, Courtens AM, Zwakhalen SM, van Kleef M, de Witte LP. Self-management support intervention to control cancer pain in the outpatient setting: a randomized controlled trial study protocol. BMC Cancer. 2015 May 19;15:416. doi: 10.1186/s12885-015-1428-1.

MeSH Terms

Conditions

PainCancer Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 29, 2014

First Posted

January 8, 2015

Study Start

February 1, 2014

Primary Completion

June 1, 2015

Study Completion

August 1, 2015

Last Updated

January 8, 2015

Record last verified: 2015-01

Locations