NCT02333630

Brief Summary

The investigators aim to study the clinical efficacy of a mobile health application, AsthmaCare, and it's impact on long term health outcomes for asthma. AsthmaCare is a novel application developed by members of the study team that was previously studied in a pilot study of 21 children/teenagers 9-16 years old. During the 30 day pilot study, there was universal usage and acceptance by all participants of this novel form of technology and asthma management. This current study aims to measure clinical outcomes for users of the app.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
200

participants targeted

Target at P50-P75 for not_applicable asthma

Timeline
Completed

Started Nov 2014

Typical duration for not_applicable asthma

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2014

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

December 17, 2014

Completed
21 days until next milestone

First Posted

Study publicly available on registry

January 7, 2015

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2016

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2017

Completed
2.9 years until next milestone

Results Posted

Study results publicly available

March 11, 2020

Completed
Last Updated

March 11, 2020

Status Verified

March 1, 2020

Enrollment Period

2 years

First QC Date

December 17, 2014

Results QC Date

March 15, 2018

Last Update Submit

March 3, 2020

Conditions

Keywords

asthma

Outcome Measures

Primary Outcomes (1)

  • Number of Emergency Room Visits Secondary to Asthma Exacerbation

    Number of emergency room visits for asthma 6 months following study enrollment and randomization

    6 months

Secondary Outcomes (3)

  • Number of Asthma Exacerbations

    6 months

  • Hospitalizations

    6 months

  • Frequency of Use of the Mobile Health Application

    6 months

Study Arms (2)

AsthmaCare intervention

EXPERIMENTAL

Participants randomized to this arm will have the AsthmaCare app downloaded to their mobile device at time of study recruitment. They will have access to AsthmaCare indefinitely after enrollment.

Other: AsthmaCare mobile health application

Control group

ACTIVE COMPARATOR

Participants randomized to this arm will receive a link to a website containing asthma education videos and information. They will be able to access this link at their discretion.

Other: Asthma education

Interventions

Personalized, interactive mobile health application designed to send daily medication reminders and assist with self management

AsthmaCare intervention

A website with links to written asthma education and videos

Control group

Eligibility Criteria

Age6 Months - 21 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Physician diagnosis of persistent asthma defined by treatment with at least one daily controller medication
  • Fluent English speaking
  • Subject must have access to an iOS or Android device in order to download and use the mobile health application
  • At least one Emergency Department or Urgent Care visit due to asthma exacerbation in the 12 months prior to enrollment

You may not qualify if:

  • No prescription/recommendation to use a daily controller medication
  • Non-English speaking
  • Lack of access to an iOS or Android device
  • Current or prior use of AsthmaCare mobile health application at any time. Research assistant will assess by reviewing beforehand a complete list of people who have already downloaded the app

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (6)

  • Martinez-Perez B, de la Torre-Diez I, Lopez-Coronado M. Mobile health applications for the most prevalent conditions by the World Health Organization: review and analysis. J Med Internet Res. 2013 Jun 14;15(6):e120. doi: 10.2196/jmir.2600.

    PMID: 23770578BACKGROUND
  • Huckvale K, Car M, Morrison C, Car J. Apps for asthma self-management: a systematic assessment of content and tools. BMC Med. 2012 Nov 22;10:144. doi: 10.1186/1741-7015-10-144.

    PMID: 23171675BACKGROUND
  • Free C, Phillips G, Galli L, Watson L, Felix L, Edwards P, Patel V, Haines A. The effectiveness of mobile-health technology-based health behaviour change or disease management interventions for health care consumers: a systematic review. PLoS Med. 2013;10(1):e1001362. doi: 10.1371/journal.pmed.1001362. Epub 2013 Jan 15.

    PMID: 23349621BACKGROUND
  • Marcano Belisario JS, Huckvale K, Greenfield G, Car J, Gunn LH. Smartphone and tablet self management apps for asthma. Cochrane Database Syst Rev. 2013 Nov 27;2013(11):CD010013. doi: 10.1002/14651858.CD010013.pub2.

    PMID: 24282112BACKGROUND
  • Chan AH, Reddel HK, Apter A, Eakin M, Riekert K, Foster JM. Adherence monitoring and e-health: how clinicians and researchers can use technology to promote inhaler adherence for asthma. J Allergy Clin Immunol Pract. 2013 Sep-Oct;1(5):446-54. doi: 10.1016/j.jaip.2013.06.015. Epub 2013 Aug 30.

    PMID: 24565615BACKGROUND
  • Stukus DR, Farooqui N, Strothman K, Ryan K, Zhao S, Stevens JH, Cohen DM. Real-world evaluation of a mobile health application in children with asthma. Ann Allergy Asthma Immunol. 2018 Apr;120(4):395-400.e1. doi: 10.1016/j.anai.2018.02.006. Epub 2018 Feb 13.

MeSH Terms

Conditions

Asthma

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Results Point of Contact

Title
David Stukus, MD
Organization
Nationwide Children's Hospital

Study Officials

  • David Stukus, M.D.

    Nationwide Children's Hospital

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

December 17, 2014

First Posted

January 7, 2015

Study Start

November 1, 2014

Primary Completion

November 1, 2016

Study Completion

May 1, 2017

Last Updated

March 11, 2020

Results First Posted

March 11, 2020

Record last verified: 2020-03