NCT02333422

Brief Summary

The investigators therefore propose a pilot study to establish the effectiveness of NIRS Neurofeedback training in reducing the intensity of ADHD symptom expression on children, improvement of the cognitive and global functions associated with ADHD, effects on cerebral blood perfusion in the cortex and safety plus possible unknown side-effects.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
10

participants targeted

Target at below P25 for phase_2

Timeline
Completed

Started Jul 2014

Shorter than P25 for phase_2

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2014

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

December 30, 2014

Completed
8 days until next milestone

First Posted

Study publicly available on registry

January 7, 2015

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2015

Completed
Last Updated

January 7, 2015

Status Verified

January 1, 2015

Enrollment Period

1 year

First QC Date

December 30, 2014

Last Update Submit

January 6, 2015

Conditions

Keywords

NIRS NeurofeedbackAttention Deficit Hyperactivity DisorderNear Infrared SpectroscopyADHD

Outcome Measures

Primary Outcomes (1)

  • Diagnostic and severity measure

    Swanson, Nolan and Pelham Questionnaire version IV (SNAPIV)

    3 months

Secondary Outcomes (10)

  • Basic processing

    3 months

  • Inhibition control

    3 months

  • Conflict Control

    3 months

  • Time processing

    3 months

  • Delay Aversion

    3 months

  • +5 more secondary outcomes

Study Arms (1)

NIRS Neurofeedback

EXPERIMENTAL

NIRS Neurofeedback training of frontal and pre frontal lobes activation. The intervention consist of 24 NIRS neurofeedback sessions over 12 weeks, 2 sessions per week.

Other: NIRS Neurofeedback

Interventions

The sensor will be placed on 4 specific regions defined by the International 10/20 System for Electrode Placement. F7, Fp1, Fp2 and F8. Each region will be initially trained for 4 minutes, with the eyes open, gradually increasing training time throughout the sessions to a maximum of 10 minutes. Training will amount to 24 sessions, occurring 2 times per week over a period of 3 moths. The procedure will be interrupted at any time, should the subject demonstrate the desire to stop.

Also known as: Near Infrared Spectroscopy Neurofeedback
NIRS Neurofeedback

Eligibility Criteria

Age7 Years - 12 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Diagnosed with ADHD clinically.
  • Cognitive dysfunction: ≥11/2; standard deviation above norm in at least two neuropsychological measurements: executive functions (inhibitory control), gratification aversion and time processing
  • Not having used ADHD medication in at least three months with parental consent for not treating ADHD with medication

You may not qualify if:

  • Existence of another co-morbid mental disorder which is clinically relevant and demands treatment
  • IQ \< 80

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital de Clínicas de Porto Alegre

Porto Alegre, Rio Grande do Sul, 90035-003, Brazil

RECRUITING

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior DisordersNeurodevelopmental DisordersMental Disorders

Study Officials

  • Luis AP Rohde

    Hospital de Clínicas de Porto Alegre

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
phase 2
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 30, 2014

First Posted

January 7, 2015

Study Start

July 1, 2014

Primary Completion

July 1, 2015

Study Completion

July 1, 2015

Last Updated

January 7, 2015

Record last verified: 2015-01

Locations