In Vivo Raman Spectroscopy of Human Capillary Beds

NCT02333136 | Terminated

• 1 other identifier: 327074-1
• Study Type: observational
• Target: 5
• Locations: 1 country
• Sites: 1

Brief Summary

The LighTouch device shines imperceptible red light into the skin and measures the light that comes back out using the method of Raman Spectroscopy. Some of this light is color shifted and some is not. Using a proprietary numerical recipe, the LighTouch device combines the signals in this remitted light and calculates hematocrit, glucose, protein and potentially other analytes. Thus the LighTouch device produces information without painful physical insult to the patient and can trend changes in these blood analytes in order to predict the need for intervention.

Conditions

Anemia

Outcome Measures

Primary Outcomes (1)

• correlation with actual measured hematocrit

  2 hours during dialysis

Study Arms (1)

IVRS studied

subjects will be monitored for changes in hematocrit based on results of in vivo raman spectroscopy scatter

Device: raman spectroscopy (LighTouch)

Interventions

raman spectroscopy (LighTouch) DEVICE

near infrared light will be shone upon a fingerbed capillary and light scatter measured using in vivo raman spectroscpy

IVRS studied

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

stabel dialysis patients

You may qualify if:

• adult stable on dialysis and able to consent

You may not qualify if:

• inability to acquire IVRS signal

Sponsors & Collaborators

• State University of New York - Upstate Medical University: lead

Study Sites (1)

University Dialsyis Center

Syracuse, New York, 13210, United States

Location

MeSH Terms

Conditions

Anemia

Interventions

Spectrum Analysis, Raman

Condition Hierarchy (Ancestors)

Hematologic Diseases; Hemic and Lymphatic Diseases

Intervention Hierarchy (Ancestors)

Scattering, Radiation; Chemistry Techniques, Analytical; Investigative Techniques; Spectrum Analysis

Study Officials

• Joseph Chaiken, PhD

  Syracuse University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 25, 2014
• First Posted: January 7, 2015
• Study Start: August 1, 2012
• Primary Completion: January 1, 2024
• Study Completion: January 1, 2024
• Last Updated: April 18, 2024

Record last verified: 2024-04

Locations

US (1)