NCT02331992

Brief Summary

Obstructive Sleep Apnea (OSA) is a common sleep disordered breathing condition effecting around 2-4% of the middle aged population and is characterized by periodic collapse of the upper airway during sleep. Continuous Positive Airway Pressure (CPAP) is the primary treatment for patients with OSA. Despite the effectiveness of CPAP in abolishing upper airway obstruction, acceptance of and adherence with therapy has been sub-optimal. Over the past decade, considerable research has focused on determining the factors responsible for poor CPAP adherence. Two key areas have been identified: patient-reported symptoms, including mask discomfort, pressure intolerance and nasal symptoms and the importance of patient education and support. In addition we know that the patient experience during the crucial first days and weeks of their journey predicts longer term adherence. This study investigates the ability of an automated program that assists patients towards continuous positive airway pressure (CPAP) therapy adherence.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
34

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Feb 2015

Shorter than P25 for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 4, 2015

Completed
2 days until next milestone

First Posted

Study publicly available on registry

January 6, 2015

Completed
26 days until next milestone

Study Start

First participant enrolled

February 1, 2015

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2015

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2015

Completed
3.2 years until next milestone

Results Posted

Study results publicly available

October 29, 2018

Completed
Last Updated

October 29, 2018

Status Verified

February 1, 2018

Enrollment Period

5 months

First QC Date

January 4, 2015

Results QC Date

December 2, 2015

Last Update Submit

February 4, 2018

Conditions

Keywords

Continuous Positive Airway Pressure

Outcome Measures

Primary Outcomes (1)

  • Participant Providing Feedback

    Participants will be provided questionnaires so as to provide program feedback.

    1 month

Secondary Outcomes (1)

  • Healthcare Provider Feedback

    1 month

Study Arms (1)

Positive airway pressure adherence program

EXPERIMENTAL

Participants will be enrolled in the automated adherence program and will receive supportive messages while they use CPAP as prescribed by their healthcare provider. These messages are designed to aid the participant towards therapy adherence.

Behavioral: Adherence program

Interventions

Participants will receive supportive messages while enrolled in the program.

Positive airway pressure adherence program

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • ≥ 18years of age
  • Diagnosed with OSA (AHI \>5 events/hour) and eligible for CPAP (fixed or auto) treatment under local requirements
  • Naïve to CPAP therapy, i.e. have not been prescribed CPAP in the past 5 years
  • Own a mobile phone, and has reliable mobile network coverage at their home.
  • Either: the participant will use a modem; OR the participant has access to a home internet connection (either their own, or a neighbours or friend etc) and is willing to perform a home upload.

You may not qualify if:

  • Contraindicated for CPAP therapy
  • Medically unstable condition/diagnosis that is not yet under control
  • Co-existing sleep disorder (however clinically diagnosed insomnia can be included in the study)
  • Periodic Limb Movement Arousal Index (PLMA) greater than 15/hr during the diagnostic study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Alabama Sleep Clinic

Huntsville, Alabama, 35801, United States

Location

IV Care & Respiratory

Belleville, Illinois, 62223, United States

Location

SleepMed of South Carolina

Columbia, South Carolina, 29201, United States

Location

MeSH Terms

Conditions

Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Results Point of Contact

Title
Clinical Research Scientist
Organization
Fisher & Paykel Healthcare

Study Officials

  • Hamish Collie, MHlthSc

    Fisher & Paykel Healthcare

    STUDY CHAIR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 4, 2015

First Posted

January 6, 2015

Study Start

February 1, 2015

Primary Completion

July 1, 2015

Study Completion

September 1, 2015

Last Updated

October 29, 2018

Results First Posted

October 29, 2018

Record last verified: 2018-02

Locations