NCT02323568

Brief Summary

This project is part of a large multicenter multidisciplinary program that will thoroughly explore the needs and difficulties of patients with BCR as well as those involved in their care. The results of this research program will propose recommendations for better structure and understand the follow up of these patients. From the limited data in the literature, the long-term remission in patients with ovarian cancer reported a significant and persistent fatigue, poor QoL, disorders of sexuality as well as somatic and mental illness; consumption is also a medical records for these patients. In this context, our team has initiated a large case-control study to assess fatigue (identified major problem in the long-term remission in patients with ovarian cancer), QoL and rehabilitation of patients in remission from an epithelial ovarian cancer (regardless of the stage of cancer at diagnosis, early or advanced) 3 years after the initial treatment, compared with women of the same age without ovarian cancer or serious chronic disease , from the general population. Patients and controls complement standardized and validated self-administered questionnaire (part 1). This study investigated 215 patients in long remission from ovarian cancer compared to 215 women of the same age without cancer. Recruitment of patients is currently underway, in close collaboration with teams from the Group GINECO very involved in this project. Following this step, an additional component is planned: it is to offer patients who participated in part 1, a specific gynecological consultation to assess in detail the effects of the treatments in order to better meet the needs of patients .dropoff window

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
179

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Dec 2014

Geographic Reach
1 country

18 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2014

Completed
10 days until next milestone

First Submitted

Initial submission to the registry

December 11, 2014

Completed
12 days until next milestone

First Posted

Study publicly available on registry

December 23, 2014

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2016

Completed
Last Updated

February 10, 2017

Status Verified

September 1, 2015

Enrollment Period

1.6 years

First QC Date

December 11, 2014

Last Update Submit

February 9, 2017

Conditions

Keywords

ovarian cancerquality of liferemission more than 3 years

Outcome Measures

Primary Outcomes (1)

  • Physical sequelae measured by the functional and biological effects

    At inclusion

Study Arms (1)

Gynecological consulation

OTHER
Other: Gynecological consultation

Interventions

Gynecological consulation

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age\> 18 years;
  • Patients who received optimal treatment (surgery, chemotherapy ...)
  • Patients with epithelial ovarian cancer after first-line treatment;
  • Patients without other cancer (except basal cell skin carcinoma and breast cancer in situ);
  • Patients without clinical relapse, biological or radiological documented at least 3 years after the initial treatment (from the end date of first line chemotherapy);
  • The interviews treatments are not recognized in the period;
  • Patients may be included regardless of the stage of cancer at diagnosis (early or late)
  • Patients who have signed their written consent to participate in the part 2 of the study Vivrovaire;
  • Patients who participated in part 1 of Vivrovaire study.

You may not qualify if:

  • Psychiatric pathology can disrupt the conduct of the study or to prevent the interpretation of results;
  • Persons deprived of liberty;
  • Major subject to a measure of legal protection or unable to consent.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (18)

CHU

Besançon, 25030, France

Location

Institut Bergonie

Bordeaux, 33076, France

Location

Polyclinique Bordeaux Nord

Bordeaux, 33077, France

Location

CHU

Caen, 14033, France

Location

Centre François Baclesse

Caen, 14076, France

Location

Centre Hospitalier

Cholet, France

Location

CHU Grenoble

La Tronche, 38700, France

Location

Centre Oscar Lambret

Lille, 59020, France

Location

Centre Léon Bérard

Lyon, 69008, France

Location

Institut régional du cancer

Montpellier, 34298, France

Location

Centre Antoine Lacassagne

Nice, 06189, France

Location

Hôpital Cochin

Paris, 75014, France

Location

Hôpital Européen Georges Pompidou

Paris, 75015, France

Location

Institut Jean Godinot

Reims, 51100, France

Location

Institut de Cancérologie de l'Ouest

Saint-Herblain, 44805, France

Location

GHPSO

Senlis, 60309, France

Location

Institut de cancérologie de Lorraine

Vandœuvre-lès-Nancy, 54519, France

Location

Institut Gustave Roussy

Villejuif, 94805, France

Location

MeSH Terms

Conditions

Carcinoma, Ovarian EpithelialOvarian Neoplasms

Condition Hierarchy (Ancestors)

CarcinomaNeoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasmsEndocrine Gland NeoplasmsNeoplasms by SiteOvarian DiseasesAdnexal DiseasesGenital Diseases, FemaleFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesGenital Neoplasms, FemaleUrogenital NeoplasmsGenital DiseasesEndocrine System DiseasesGonadal Disorders

Study Officials

  • Florence JOLY, PhD

    Centre François Baclesse

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 11, 2014

First Posted

December 23, 2014

Study Start

December 1, 2014

Primary Completion

July 1, 2016

Study Completion

July 1, 2016

Last Updated

February 10, 2017

Record last verified: 2015-09

Locations